Close
Close

Magic™ Recombinant Human MARCH2 Membrane Protein in Virus-Like Particles (MP-VLPs) (CAT#: S01YF-0622-KX121)

Datasheet
This product is recombinant Human MARCH2 in VLPs form. This product is produced from HEK293 by co-expressing the retroviral structural core polyprotein (gag) and the target membrane protein. MP-VLPs display highly-expressed copies of membrane proteins in their native conformation, providing an alternative to membrane protein stable cell lines, membrane preparations, detergent-solubilized proteins and other membrane protein preparation strategies. MP-VLPs can be used for a wide range of applications in antibody production, antibody discovery, antibody characterization, binding assays and functional assays.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MARCH2
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 2
  • Sequence
  • MTTGDCCHLPGSLCDCSGSPAFSKVVEATGLGPPQYVAQVTSRDGRLLSTVIRALDTPSDGPFCRICHEGANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEFAVEKRPRPLTEWLKDPGPRTEKRTLCCDMVCFLFITPLAAISGWLCLRGAQDHLRLHSQLEAVGLIALTIALFTIYVLWTLVSFRYHCQLYSEWRKTNQKVRLKIREADSPEGPQHSPLAAGLLKKVAEETPV

Product Description

  • Application
  • ELISA; Antibody Production; Antibody Discovery; Antibody Characterization; Binding Assays; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • 10xHis tag at the C-terminus
  • Protein Format
  • Membrane Protein-Virus Like Particles (MP-VLPs)
  • Buffer
  • PBS, 6% Trehalose, pH 7.4

Target

  • Target Protein
  • MARCH2
  • Full Name
  • Membrane associated ring-CH-type finger 2
  • Introduction
  • MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking.
  • Alternative Names
  • MARCH2; RNF172; HSPC240; MARCH-II; E3 ubiquitin-protein ligase MARCHF2; E3 ubiquitin-protein ligase MARCH2; RING finger protein 172; RING-type E3 ubiquitin transferase MARCH2; RING-type E3 ubiquitin transferase MARCHF2; membrane associated ring finger 2; membrane-associated RING finger protein 2; membrane-associated RING-CH protein II; membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase

Customer reviews and Q&As    

Related Products
Online Inquiry
CONTACT US
USA:
Europe:
Germany:
Call us at:
USA:
UK:
Germany:
Fax:
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us
© 2024 Creative Biolabs. | Contact Us