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Magic™ Recombinant Mouse Hvcn1 Membrane Protein in Virus-Like Particles (MP-VLPs) (CAT#: S01YF-0622-KX102)

This product is recombinant Mouse Hvcn1 in VLPs form. This product is produced from HEK293 by co-expressing the retroviral structural core polyprotein (gag) and the target membrane protein. MP-VLPs display highly-expressed copies of membrane proteins in their native conformation, providing an alternative to membrane protein stable cell lines, membrane preparations, detergent-solubilized proteins and other membrane protein preparation strategies. MP-VLPs can be used for a wide range of applications in antibody production, antibody discovery, antibody characterization, binding assays and functional assays.

Product Specifications

  • Host Species
  • Mouse
  • Target Protein
  • Hvcn1
  • Protein Length
  • Full length
  • Protein Class
  • Ion channel
  • TMD
  • 4
  • Sequence
  • MTSHDPKAVTRRTKVAPTKRMSRFLKHFTVVGDDYHTWNVNYKKWENEEEEEEPAPTSAEGEGNAEGPDAEAGSASTPRQSLDFRSRLRKLFSSHRFQVIIICLVVLDALLVLAELLLDLKIIEPDEQDYAVTAFHYMSFAILVFFMLEIFFKIFVFRLEFFHHKFEILDAFVVVVSFVLDLVLLFKSHHFEALGLLILLRLWRVARIINGIIISVKTRSERQILRLKQINIQLATKIQHLEFSCSEKEQEIERLNKLLKQNGLLGDVN

Product Description

  • Application
  • ELISA; Antibody Production; Antibody Discovery; Antibody Characterization; Binding Assays; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • 10xHis tag at the C-terminus
  • Protein Format
  • Membrane Protein-Virus Like Particles (MP-VLPs)
  • Buffer
  • PBS, 6% Trehalose, pH 7.4

Target

  • Target Protein
  • Hvcn1
  • Full Name
  • Hydrogen voltage-gated channel 1
  • Introduction
  • Enables identical protein binding activity and voltage-gated proton channel activity. Involved in response to pH and response to zinc ion. Acts upstream of or within proton transmembrane transport. Predicted to be located in apical plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human HVCN1 (hydrogen voltage gated channel 1).
  • Alternative Names
  • BTS; HV1; Vsop.; mVSOP; AI450555; 0610039P13Rik; voltage-gated hydrogen channel 1; voltage sensor domain-only protein

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