Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsHamster is an important rodent laboratory animal, which ranks 4th among rodent laboratory animals after mice, rats, and guinea pigs in terms of use and applicability. Hamsters play an important role in many areas of biomedical research, such as tissue transplantation studies, diabetes research, and studies on microcirculation and vascular reactivity. Compared to mice and rats, hamsters are more evolutionarily distantly related. Therefore, hamster antibodies are uniquely suited for a number of research areas. Based on our rich field experience and advanced monoclonal hamster antibody preparation platform, Creative Biolabs provides comprehensive antibody discovery services to support monoclonal hamster antibody production.
Hamsters have a wide range of applications in biomedical research. The first is the application in the field of tumors. Hamsters are very sensitive to viruses that can induce tumors, and tumor tissues inoculated into the oral buccal sac are easy to grow and easy to observe. These characteristics make hamsters the most commonly used animals in oncology research. In addition, hamsters are morphologically and clinically similar to human pancreatic cancer and are the only animal model capable of inducing pancreatic cancer. Secondly, hamsters have a strong reproductive ability, with late spring and early fall as their peak breeding seasons. Golden hamsters mature early, reaching sexual maturity in 30–32d. The sexual cycle of hamsters is very short, only 4–5d, which is the shortest among rodents, and each time can last 10 hours. The estrous cycle of hamsters is very accurate. These characteristics make hamsters particularly suitable for reproductive physiology research. Thirdly, in vitro culture of hamster tissue cells makes it easy to establish diploid cell lines. It is particularly suitable for tissue culture studies. And hamster kidney cells can be made into cell cultures to inoculate viruses for isolation or preparation of vaccines. For example, BHK-21 cells are hamster kidney fibroblasts, which can be used for the proliferation and purification of various viruses. In addition, hamster chromosomes are large, few in number, and easily indentifiable from each other. Therefore, they are excellent materials for studying chromosome aberrations and chromosome replication mechanisms. Fourthly, hamsters have few spontaneous infections but are sensitive to experimentally induced morbidity. Hamsters play an important role in the study of the pathogenesis and isolation of the source of diseases such as pediatric measles virus, amoeba, leishmania, and trichinella. Fifth, the development of tooth decay in hamsters is closely related to the composition of the feed and the type and number of oral microorganisms and is therefore widely used in dental (e.g., caries) research. Sixth, hamsters are also vital in the field of nutritional research. Hamsters are very sensitive to vitamin deficiencies. Therefore, it is commonly used in nutritional studies of riboflavin, vitamin A, vitamin E, and vitamin B2 deficiencies.
Currently, the techniques commonly used to prepare monoclonal hamster antibodies are hybridoma technology and phage display technology. After more than 40 years of development and improvement, the process of preparing monoclonal hamster antibodies based on hybridoma technology has become very mature. Based on phage display technology, rich and diverse specific antibodies can be obtained directly through antigen immunization. Monoclonal hamster antibodies can be rapidly obtained by phage display library construction and phage display library screening. Immune antibody libraries are an important type of phage antibody library, which are constructed after immunization with antibody genes from donor B lymphocytes and a good tool for studying the humoral immunity of an organism to a certain antigen. An immune-antibody library can be enriched for antigen-specific antibodies, and a high rate of antibody libraries encoding functional antibodies that recognize specific immunogens means that functional antibodies and their genes against immunogens can be screened from libraries with a small library capacity.
Creative Biolabs has a wealth of knowledge and experience in monoclonal antibody discovery. We would be happy to share with you our knowledge and experience related to monoclonal hamster antibody discovery.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
