Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
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Creative Biolabs is able to discover naïve ferret monoclonal antibodies via our specific Native™ Antibody Discovery Platform.
Ferret (Mustela putorius furo) is a kind of domestic animals belong to the family Mustelidae (also includes weasel, otter and mink). In biological research, ferret is well recognized as the indispensable mammalian model in the investigation of influenza viruses. Because of their relatively small size, similar lung physiology with human and other clinical features associated with human diseases, ferret is obviously an attractive species for the studies related to virus-host interactions. Nonetheless, the immune system of this species has not been well characterized, implicating ferret a potential role as novel host species for antibody discovery. Compared with other small laboratory animals (e.g. mice, rats, hamsters, rabbits, etc.), ferret has relatively distant evolutionary relationships which may induce better immune response for some antigens that are hardly recognized by other species. In addition, compared with other large laboratory animals (e.g. dogs, monkeys, goats, etc.), ferrets are relatively inexpensive but sufficiently large for periodic blood collection for either antibody discovery or other immune assays. The DNA sequences between ferret and canine (dog) are highly homological to each other, so ferret host responses to some canine reagents can be successfully assessed. Moreover, studies revealed several immunological cross-reactivities between ferrets and human, for instance some antibodies against human CD markers can also react with CD markers on ferret peripheral blood leucocytes (PBLs). In this way, ferret is considered as a kind of useful outbred experimental animal which may especially contribute to the understanding of human infection.
With decades’ experience in antibody research and development, scientists from Creative Biolabs have developed the unique Native™ Antibody Discovery Platform to acquire ferret monoclonal antibodies with the most natural features. This platform is mainly based on the antigen-specific B lymphocytes cytometry technology, which can isolate a plenty of monoclonal antibody candidates with native paired heavy- and light-chains. In addition, monoclonal antibodies selected by this platform matured in vivo, thereby possessing relative higher specificity, affinity and stability than antibodies that produced by other traditional technologies. Currently, Creative Biolabs is able to utilize this platform to discover monoclonal antibodies from various species, including but not limited to ferret, mink, rodents, rabbits, monkey, chicken, dog, camel, shark and alligator.
Creative Biolabs is a long-term expert in the field of antibody discovery and development. Over the past decades, we have generated thousands of different antibodies for our customers all over the world. Our scientists are confident in providing the most appropriate customized services to achieve high-quality antibodies for our clients’ satisfaction.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
