Q: What makes the Human GPIHBP1 Autoantibody (IgG) ELISA kit highly sensitive?
A: The Human GPIHBP1 Autoantibody (IgG) ELISA kit achieves its high sensitivity through the precise calibration of its components, including a labeled antibody concentration and a specialized TMB solution. The kit is designed to detect GPIHBP1 Autoantibody concentrations as low as 0.001 U/mL, making it one of the most sensitive assays available for this purpose. This sensitivity is crucial for detecting even the most minimal levels of autoantibodies in human plasma or serum, providing researchers and clinicians with a reliable tool for studying and diagnosing conditions related to GPIHBP1 autoantibodies.
Q: Can the Human GPIHBP1 Autoantibody (IgG) ELISA kit be used with any type of human plasma or serum?
A: Yes, the Human GPIHBP1 Autoantibody (IgG) ELISA kit is versatile in its sample requirements, compatible with serum, EDTA-plasma, heparin plasma, and post-heparin EDTA-plasma. This flexibility allows researchers to use the kit across a wide range of sample types, ensuring broad applicability in various experimental setups and clinical diagnostics. By accommodating different types of plasma and serum, the kit enhances its utility in diverse research and healthcare settings, facilitating the detection and study of GPIHBP1 autoantibodies in multiple patient populations.
Q: What role does GPIHBP1 play in the body, and why is it important to measure GPIHBP1 autoantibodies?
A: GPIHBP1 is a critical protein in the capillary endothelial cells that facilitates the lipolytic processing of triglyceride-rich lipoproteins. It acts as a transporter for lipoprotein lipase (LPL) from the subendothelial spaces to the capillary lumen, playing a vital role in lipid metabolism. Measuring GPIHBP1 autoantibodies is essential because their presence can interfere with this process, potentially leading to hyperlipoproteinemia, type 1D, and other metabolic disorders. By detecting these autoantibodies, researchers and clinicians can gain insights into autoimmune processes affecting lipid metabolism and devise appropriate therapeutic strategies.
Q: How should the ELISA kit be stored?
A: Storage instructions typically include short-term storage temperatures (e.g., 4°C) and guidelines for longer-term storage, which might require freezing. Adhering to these guidelines ensures the kit's components remain stable and effective.
Datasheet
Lipoprotein lipase– Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 (LPL–GPIHBP1) interactions at the capillary lumen.