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ImmunoArrayᵀᴹ Autoantibody Detection Microarray Service (CAT#: NA-0726-FY12)
Developed by Creative Biolabs, the service leverages an advanced, high-sensitivity protein microarray platform to profile autoantibodies against 82 carefully curated antigens. By preserving the native conformation of these antigens on a 3D surface, the service provides an efficient, low-sample-rate, and cost-effective solution for large-scale immune profiling. It serves as a powerful tool for discovering clinical antibody biomarkers, decoding disease pathogenesis, and establishing multi-parametric diagnostic and prognostic models.
| Specifications | |
|---|---|
| Size | 16-sample format per slide; detects>120 targets per well (including 82 disease-related antigens + internal controls). |
| Throughput Level | High-throughput (processes 16 samples per slide simultaneously, with support for parallel operations across multiple slides). |
| Protein Count | 82 types of high-quality purified antigens. |
| Proteome Coverage | Focused array targeting 82 critical antigens highly correlated with systemic/organ-specific autoimmune diseases and infections based on published research. |
| Arraying Technology | High-sensitivity antigen microarray technology (protein microarray) where antigens are precisely immobilized onto a three-dimensional (3D) coated surface; uses fluorescent secondary antibodies and fluorescence scanning for signal detection. |
| Quality Control | Each array integrates internal Ig and anti-Ig control pairs to ensure reliable data normalization and relative quantification. |
| Features | High Multiplexing: Screens>120 autoantibodies per well (vs. just 1 via traditional ELISA). Ultra-low Sample Volume: Requires only 5 μL of serum or other body fluids. Multi-Isotype Detection: Simultaneously detects two antibody types (e.g., IgG, IgM, or IgA) on a single array. High Sensitivity & Wide Dynamic Range: Signal intensity spans from 1 to 65000. Cost-Effective: Priced at less than 1/10 of traditional ELISA kits. Semi-Quantitative: Enables relative quantification based on standard curves. |
| Application Fields | Autoimmune Diseases: SLE, RA, diabetes, MCTD, Sjögren's syndrome, scleroderma, polymyositis, dermatomyositis, etc. Other Pathology Areas: Allergic diseases, infectious diseases, neurological disorders, and cancer biomarker discovery. Translational & Clinical Research: Vaccine R&D and post-vaccination monitoring (e.g., SARS-CoV-2, RSV, influenza), organ transplantation evaluation, immunomodulatory therapy toxicity monitoring, drug screening, and clinical trials. |
For Research Use Only | Not For Clinical Use
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