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ImmunoArrayᵀᴹ Autoimmune Myocarditis and Myositis-Related Autoantibody Detection Service (Antigen Microarray) (CAT#: NA-0726-FY10)
A high-sensitivity, cost-effective, and highly multiplexed antigen microarray platform tailored for translational medicine and cardiovascular/muscular scientific research. By coating 120 high-quality purified cardiac, muscle, and neuronal-muscle transmitter antigens onto a 3D chip surface to maintain native conformation, the service profiles complex antibody patterns using as little as 5 μl of serum or other body fluids. It is widely used to discover biomarkers and establish multi-parametric models for early disease warning, diagnosis, and efficacy tracking.
| Specifications | |
|---|---|
| Throughput Level | High throughput (Capable of processing 16 samples simultaneously per slide, with multiple slides operable in parallel) |
| Protein Count | Contains 120 antigens selected based on comprehensive literature searches/Capable of profiling more than 120 autoantibodies per well |
| Proteome Coverage | Broad coverage of targets related to the cardiovascular and muscular systems, including cardiac antigens, muscle antigens, and neuronal-muscle transmitter antigens. |
| Purification Method | Utilizes high-quality purified antigens. (Specific purification protocols are not detailed) |
| Arraying Technology | High-sensitivity antigen microarray technology (Antigens are orderly immobilized on the 3D surface of a microchip; flexible enough to integrate proteins, peptides, and nucleic acids onto a solid carrier surface) |
| Quality Control | Each array contains internal Ig and anti-Ig controls for normalization and quantification; offers high sensitivity with a dynamic range of 1 to 65000; features semi-quantitative analysis based on standard curves. Dual-color/multiplexed fluorescent secondary antibodies enable the detection of different antibody types and subtypes within a single assay to minimize sample usage. |
| Application Fields | 1. Disease Warning & Diagnosis: Autoimmune myocarditis, myositis, systemic and organ-specific autoimmune diseases (e.g., SLE, Rheumatoid Arthritis, Diabetes, MCTD, Sjögren's syndrome, Scleroderma, Polymyositis, Dermatomyositis), Allergies, Infectious diseases, Neurological/brain disorders, and Cancers. 2. Treatment & Clinical Research: Selection of therapeutic methods, treatment efficacy evaluation, prognosis analysis, drug screening, clinical trials, and organ transplantation outcome assessment. 3. Vaccine Development & Safety: Viral vaccine development and post-vaccination monitoring for autoimmune reactions (e.g., SARS-CoV-2, other coronavirus strains, Influenza, and RSV). 4. Biomarker Discovery: Mass-scale autoantibody profiling to discover clinically valuable antibody markers and investigate disease pathogenesis. |
DatasheetFor Research Use Only | Not For Clinical Use
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