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ImmunoArrayᵀᴹ Common Autoimmune Disease-Related Autoantibody Detection Service (Antigen Microarray) (CAT#: NA-0726-FY9)
A high-sensitivity, cost-effective, and highly multiplexed antigen microarray service designed for translational medicine and scientific research. By utilizing high-quality purified antigens immobilized on a 3D surface to preserve their native conformation, the platform can profile dozens of disease-related autoantibodies simultaneously. Requiring as little as 5 μl of serum or other body fluids, it enables comprehensive immune profiling to construct multi-parametric models for early disease detection, prognosis, and therapeutic evaluation.
| Specifications | |
|---|---|
| Throughput Level | High throughput (Capable of processing 16 samples simultaneously per slide, with multiple slides operable in parallel) |
| Protein Count | Contains 52 autoantigens selected based on published research findings/Capable of detecting up to 52 specific autoantibodies, and more than 120 autoantibodies per well in the wider platform. |
| Proteome Coverage | Profiles antibodies associated with a wide spectrum of autoimmune conditions, including systemic, organ-specific, and infection-related autoimmune diseases. |
| Purification Method | Utilizes high-quality purified antigens. (Specific purification protocols are not detailed) |
| Arraying Technology | High-sensitivity antigen microarray technology (Antigens are coated onto the 3D surface of a microchip; can combine proteins, peptides, and nucleic acids orderly immobilized on a solid carrier surface) |
| Quality Control | Includes internal Ig and anti-Ig controls in each array for normalization and quantification; offers high sensitivity with a dynamic range of 1 to 65000; features semi-quantitative analysis based on standard curves. Dual-color fluorescent secondary antibodies allow simultaneous detection of two antibody classes (IgG, IgM, or IgA) on a single array. |
| Application Fields | 1. Disease Warning & Diagnosis: Systemic and organ-specific autoimmune diseases (e.g., SLE, Rheumatoid Arthritis, Diabetes, MCTD, Sjögren's syndrome, Scleroderma, Polymyositis, Dermatomyositis), Allergies, Infectious diseases, Neurological/brain disorders, and Cancers. 2. Treatment & Clinical Research: Selection of therapeutic approaches, treatment efficacy evaluation, prognosis tracking, drug screening, clinical trials, and organ transplantation immunity monitoring. 3. Vaccine Safety & Development: Development of viral vaccines and monitoring of post-vaccination autoimmune adverse reactions (e.g., SARS-CoV-2, other coronavirus strains, Influenza, and RSV). 4. Biomarker Discovery: Large-scale screening to discover clinically valuable antibody markers and investigate disease pathogenesis. |
DatasheetFor Research Use Only | Not For Clinical Use
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