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ImmunoArrayᵀᴹ Human Proteome Microarray (CAT#: NA-0526-FY1)
The product stands as the world's highest-throughput functional protein microarray, displaying over 21000 unique human proteins and capturing an industry-leading 81% of the human genome. By leveraging a eukaryotic S. cerevisiae expression system, nearly 90% of these proteins are printed as full-length, biologically active molecules that retain native conformations and authentic post-translational modifications. Manufactured using advanced non-contact printing technology, the platform guarantees exceptional intra- and inter-assay consistency. It serves as an indispensable discovery engine for high-throughput screening, driving breakthroughs in autoantibody biomarker discovery, small-molecule target identification, antibody specificity profiling, and complex interactome mapping.
| Specifications | |
|---|---|
| Size | 75 mm × 25 mm (Standard microscope slide size) |
| Throughput Level | Currently the highest-throughput human proteome microarray |
| Protein Count | Contains>21000 recombinant human proteins |
| Proteome Coverage | Reaches up to 81% coverage of the human genome |
| Full-Length Protein Ratio | 89.48% are full-length proteins |
| Expression System | Soluble expression in S. cerevisiae (Baker's yeast) system |
| Purification Method | GST affinity purification |
| Arraying Technology | Advanced non-contact printing technology (ensuring superior protein uniformity across the microarray surface) |
| Quality Control | All genes are verified and confirmed by sequencing |
| Features | High Coverage & High Fidelity: Features over 80% coverage of the human proteome, with the vast majority (nearly 90%) being full-length proteins, allowing for a more authentic simulation of the natural structures of proteins in vivo. High Activity & Stability: Utilizes a eukaryotic expression system (S. cerevisiae) for soluble expression, which better ensures correct protein folding and post-translational modifications (PTMs) compared to prokaryotic systems. Combined with non-contact printing, the microarray exhibits excellent homogeneity. |
| Application Fields | Autoantibody Biomarker Screening (e.g., autoimmune diseases, immuno-oncology research) Small Molecule Drug Target Screening (identifying mechanism-of-action targets for drugs) Protein-Nucleic Acid Interactions (DNA/RNA-binding protein studies) Protein-Protein Interactions (PPI) (constructing interactome networks, host-pathogen interactions) Protein-Lipid Interactions Protein Post-Translational Modification (PTM) Studies (e.g., phosphorylation, acetylation, ubiquitination, and SUMOylation) Antibody Specificity Validation (verifying antibody off-target effects or cross-reactivity) |
DatasheetFor Research Use Only | Not For Clinical Use
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