ImmunoArrayᵀᴹ Kidney Disease-Related Autoantibody Detection Microarray Service (51-Antigen Array) (CAT#: NA-0726-FY13)

Developed by Creative Biolabs, the Kidney Disease-Related Autoantibody Detection Service leverages an advanced, high-sensitivity protein microarray platform to profile autoantibodies against 51 carefully curated antigens. By preserving the native conformation of these antigens on a 3D surface, the service provides an efficient, low-sample-rate, and cost-effective solution for large-scale immune profiling. It serves as a powerful tool for discovering clinical antibody biomarkers, decoding disease pathogenesis, and establishing multi-parametric diagnostic and prognostic models for renal and systemic autoimmune disorders.

Specifications
Size16-sample format per slide; features powerful multiplexing capable of detecting>120 targets per well (including 51 kidney-specific antigens + internal controls).
Throughput LevelHigh-throughput (processes 16 samples per slide simultaneously, with support for parallel operations across multiple slides).
Protein Count51 types of high-quality purified antigens.
Proteome CoverageFocused array targeting 51 critical antigens highly correlated with autoimmune kidney diseases and nephritis (including Lupus Nephritis [LN], Membranous Nephropathy [pMN], and ANCA-Associated Vasculitis [AAV]) selected based on published research.
Arraying TechnologyHigh-sensitivity antigen microarray technology (protein microarray) where antigens are immobilized onto a three-dimensional (3D) coated surface; uses fluorescent secondary antibodies and fluorescence scanning to detect signal intensities.
Quality ControlEach array integrates internal Ig and anti-Ig control pairs to ensure reliable data normalization and relative quantification.
FeaturesHigh Multiplexing: Screens>120 autoantibodies per well (far exceeding traditional single-target ELISA).
Ultra-low Sample Volume: Requires only 5 μL of serum or other body fluids to minimize sample consumption.
Dual-Isotype Detection: Simultaneously detects two antibody types (IgG and IgA) on a single array.
High Sensitivity & Wide Dynamic Range: Signal intensity ranges from 1 to 65000.
Cost-Effective: Priced at less than 1/10 of traditional ELISA kits.
Semi-Quantitative: Enables relative quantification based on standard curves.
Customization Flexibility: Custom antigen chips, detection, and data analysis services are available alongside the pre-made array.
Application FieldsKidney & Autoimmune Diseases: Diagnosis, monitoring, and pathogenesis research of Lupus Nephritis (LN), Membranous Nephropathy (pMN), ANCA-Associated Vasculitis (AAV), Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA), diabetes, MCTD, Sjögren's syndrome, scleroderma, polymyositis, dermatomyositis, etc. Other Pathology Areas: Allergic diseases, infectious diseases, neurological disorders, and cancer biomarker discovery. Translational & Clinical Research: Vaccine R&D and post-vaccination monitoring (e.g., SARS-CoV-2, RSV, influenza), organ transplantation evaluation, immunomodulatory therapy toxicity monitoring, drug screening, and clinical trials.
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