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ImmunoArrayᵀᴹ Neuroimmune-Related Autoantibody Detection Service (CAT#: NA-0726-FY15)
Developed by Creative Biolabs, the Neuroimmune-Related Autoantibody Detection Service utilizes an advanced, high-sensitivity protein microarray platform to efficiently profile autoantibodies against 120 literature-backed CNS antigens. By immobilizing purified proteins onto glass slides, this high-throughput, low-sample-rate service allows researchers to analyze complex autoantibody signatures cost-effectively. It serves as a powerful tool for translational medicine, aiding in early disease warning, multi-parametric diagnostic/prognostic modeling, and the acceleration of targeted therapeutics.
| Specifications | |
|---|---|
| Size | 16-sample format per slide; features high-multiplex capability detecting>120 targets per well (encompassing the 120 neuroimmune-specific antigens). |
| Throughput Level | High-throughput (processes 16 samples per slide simultaneously, with support for parallel operations across multiple slides). |
| Protein Count | Up to 120 purified proteins/antigens. |
| Proteome Coverage | Focused neuroimmunology panel consisting of 120 purified proteins thoroughly reviewed in literature and established as biomarkers or pathogenic factors associated with specific central nervous system (CNS) diseases. |
| Arraying Technology | High-sensitivity antigen microarray technology (protein microarray) where protein molecules are orderly immobilized as ligands onto the surface of solid phase glass slides; interactions are resolved using fluorescently labeled molecules and fluorescence scanning to measure spot intensities. |
| Features | High Multiplexing: Screens>120 autoantibodies simultaneously per well, far outperforming traditional single-target ELISA methods. Ultra-low Sample Volume: Requires only 5 μL of serum or other body fluids, significantly preserving clinical samples. High Flexibility: Capable of combining various antigen types (proteins, peptides, nucleic acids) to detect diverse antibody classes and subclasses. High Sensitivity & Wide Dynamic Range: Offers a robust signal dynamic range spanning from 1 to 65000. Cost-Effective: Delivers comprehensive profiles at less than 1/10 of the cost of traditional ELISA kits. Semi-Quantitative: Enables relative quantification derived from standard curves. |
| Application Fields | Neurological & CNS Disorders: Screening, biomarker discovery, and pathogenesis research of cranial nerve disorders and central nervous system impairments. Autoimmune Diseases: Profiling of systemic and organ-specific conditions such as SLE, RA, diabetes, MCTD, Sjögren's syndrome, scleroderma, polymyositis, dermatomyositis, etc. Translational & Clinical Research: Scale-driven analysis of immune responses across allergic diseases, infectious diseases, tumor immunology (cancer biomarkers), vaccine R&D/post-vaccination monitoring (e.g., SARS-CoV-2, RSV, influenza), organ transplantation evaluation, drug screening, and clinical trials. |
DatasheetFor Research Use Only | Not For Clinical Use
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