Category:
Non-Human Primate (NHP) related Antibody Products
Alpha Fetoprotein Monoclonal Antibody (ERb45) (NHP-AB170)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing mouse against alpha fetoprotein purified from serum of a hepatoma patient. It is used only in in vitro assays.
Introduction:
AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of AFP may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric, dimeric, and trimeric forms. AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Conjugate:
None
Antibody Isotype:
IgG2aκ
Applications:
Flow Cytometry; IF; IHC
Host Species:
Mouse
Species Reactivity:
Dog; Human; Monkey; Pig
Immunogen:
Alpha fetoprotein purified from serum of a hepatoma patient
Purification:
Protein G affinity chromatography
Format:
Liquid
Concentration:
0.2 mg/mL
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Storage:
Store at 4⁰C. Avoid freeze-thaw cycles.
Target:
Alpha Fetoprotein
Clone:
ERb45
Clonality:
Monoclonal
Related Disease:
High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.
Alternative Names:
a fetoglobulin; a fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin; Alpha-fetoprotein; fetoglobulin; fetoprotein; α fetoglobulin; α fetoprotein
Entrez Gene ID:
174
- Alpha Fetoprotein Monoclonal Antibody (ERb45) (NHP-AB170) Data Sheet: Detailed information. datasheet
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Your research is unique, and we understand that standard products may not always fit. Our team of experts specializes in custom NHP sample collections. We can design a tailored protocol to meet your specific research requirements, including samples with unique anticoagulant types, customized volumes, or from specific disease models.
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For research use only. Not intended for any clinical use.
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