Anti-Rhesus J chain Monoclonal Antibody (CA1A1) (NHP-AB059)

• The antibody CA1L_33e1_A1a3 recognizes human and rhesus J chain. This product is a purified mouse monoclonal antibody that reacts specifically with rhesus J chain within dimeric IgA.

Detailed Product Description

• Introduction: J chain is a small glycopeptide and is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsil and lymph node. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.
• Conjugate: None
• Antibody Isotype: IgG1
• Applications: Reference Reagents

Technical Specifications

• Host Species: Mouse
• Species Reactivity: Rhesus

Target Information

• Target: J chain
• Clone: CA1A1
• Alternative Names: IgJ chain; Immunoglobulin J chain; immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides; J chain; Joining chain of multimeric IgA and IgM