Baboon is an Old World monkey belonging to the subfamily Cercopithecinae, which is a good animal model for research and investigations in physiology and pathophysiology.
Background of Baboon
Baboons (genus Papio), are some of the world's largest monkeys. There are five species of large, robust, and primarily terrestrial monkeys belong to the baboon - olive, yellow, chacma, Guinea, and hamadryas - scattered across various habitat in Africa and Arabia. All species have long noses with nostrils at the ends; males have long dagger-like canine teeth. They have a cluster of hair on both sides of their faces and large, hairless bottoms that can turn red. These Old World monkeys don't have the same prehensile tail as other monkeys, which mean they don't use their tails like their hands. From head to bottom, baboon grows to 60 to 86 cm and the length of the tail adds an additional 41 to 58 cm. Their weight is about the same as a human child, 22 to 37 kg. Unlike other monkeys, baboons spend most of time on the ground. They are omnivorous animals and very social creatures.
Baboon in Research
As research resources, baboons are not limited. They are close to humans in evolution, showing that the offspring of complex human disease phenotypes support their further optimization of a valuable primate model. Baboon is a recently described preclinical model for the study of B. pertussis infection and may be an ideal choice for evaluating new pertussis vaccines. Due to their size and anatomical similarity to humans, baboons make an excellent model for reproductive research regarding endometrial biology, uterine receptivity and embryo implantation applicable to humans. Compared with smaller non-human primates such as rhesus or cynomolgus monkeys, baboons can perform non-invasive endometrial biopsies, embryo irrigation or transplantation and hysteroscopy using cervical uterine probes (curettes, catheters, and hysteroscopy equipment). In addition, baboons and their derived products have been widely used as genetic research models for complex diseases, and continue to be successful models for many chronic and infectious diseases. They have been further used to study contraception, tissue-engineered heart valves, epilepsy, immune system aging, sepsis, and ischemic stroke.
Creative Biolabs strives to meet the needs of the biomedical research community by providing high-quality Baboons-derived products such as whole blood, tissues and biological fluids to investigators throughout the country. Please contact us for more information.