The capuchin monkeys are New World monkeys of the subfamily Cebinae. They are the best neotropical primates at adapting to captivity and are one of the most widely used primates in ophthalmology field.
Background of Capuchin Monkey
Capuchin monkeys, also called Cebus apella or sapajou, are considered to be the smartest New World monkeys of the subfamily Cebinae, indigenous to Central and South America. They have a darkly colored body, arms, and legs with a white face, throat, and chest, and a black cap of fur on top of the head. Capuchin monkeys are agile and lean with the only 3-9 pounds of weight (1.36-4.9 kg) and 30-56 cm in length. Their tails are as long as their bodies, covered with hair and part of them can be wrapped around branches. They are integrated into many ways with humans and chimpanzees, including brain size, omnivorous and mining foraging, extensive collaborative and alliance behavior, and a reliance on social learning.
Capuchin Monkey in Research
Histologically, the retina of capuchin monkeys exhibits the same typical pattern as that of mammals. This similarity is related to the number of corneal epithelial cells and the pigmentation of vascular layer. Therefore, capuchin monkey is an important experimental model in human beings ophthalmology research. Non-human primates are the third most common transmitters of rabies to humans. Because of their wide geographical distribution of all species of Neotropical primates, capuchin monkeys may also be useful models for rabies-related studies. In capuchin monkeys, maternal exposure to light during the last three months of pregnancy may lead to premature adrenal maturation and increased plasma cortisol in newborns. Using this characteristic, studies can be focused on compensatory mechanism of response, which may help to overcome the adrenal changes during pregnancy and restore normal cortisol concentration in growing infants. In addition, the study on capuchin monkeys may provide new insights into the circadian expression patterns of Period 3 (Per3), the clock gene associated with delayed sleep phase syndrome (SDPS) and human chronotype, in different organs and its relationship with behavior, with a view to further inferring human health.
Capuchin monkey-derived products are available at Creative Biolabs in a variety of formats including whole blood, primary cells, tissue, slides, and blocks. We also provide standard formats as well as customized tissue preparations to meet your research needs. If you have a specific protocol to be followed for capuchin monkey-derived products, please contact us.