Category:
Non-Human Primate (NHP) related Antibody Products
CD3e Monoclonal Antibody (HJ21) (NHP-AB184)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing mouse against stimulated human leukocytes. It is used only in in vitro assays.
Introduction:
Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
Conjugate:
None
Antibody Isotype:
IgG2aκ
Applications:
IF
Host Species:
Mouse
Species Reactivity:
Human; Monkey
Immunogen:
Stimulated human leukocytes
Purification:
Protein G affinity chromatography
Format:
Liquid
Concentration:
0.2 mg/mL
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Storage:
Store at 4⁰C. Avoid freeze-thaw cycles.
Target:
CD3e
Clone:
HJ21
Clonality:
Monoclonal
Alternative Names:
T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T3E
Entrez Gene ID:
916
- CD3e Monoclonal Antibody (HJ21) (NHP-AB184) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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