Category:
Non-Human Primate (NHP) related Antibody Products
CD51 Monoclonal Antibody (C13R6), PE (NHP-AB101)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody conjugated with PE that was generated by immunizing mice against cell suspension containing osteoclasts from osteoclastomas. It is used only in in vitro assays.
Introduction:
CD51 represents the integrin alpha V chain that associates with integrin beta3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils, and platelets. CD51 is the most promiscuous integrin alpha subunit as it can form heterodimers with the beta1 (CD29), beta3 (CD61), beta5, beta6 and beta8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.
Conjugate:
PE
Antibody Isotype:
IgG1
Applications:
Flow Cytometry
Host Species:
Mouse
Species Reactivity:
African green Monkey; Bovine; Human; Rabbit
Immunogen:
Cell suspension containing osteoclasts from osteoclastomas
Format:
Liquid
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Storage:
Store at 4⁰C.
Target:
CD51
Clone:
C13R6
Clonality:
Monoclonal
Alternative Names:
Integrin alpha V, vitronectin receptor, VNR-alpha chain
Entrez Gene ID:
3685
- CD51 Monoclonal Antibody (C13R6), PE (NHP-AB101) Data Sheet: Detailed information. datasheet
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