Chimpanzee (Pan troglodytes) is a well-known non-human primate that is physiologically and genetically similar to humans, with greater than 98% DNA sequence homology with humans. Because of this, chimpanzees are widely used in various fields of biomedical research and have made great contributions to the study of complex diseases in humans.
Introduction of Chimpanzee
Chimpanzee (Pan troglodytes, P. troglodytes) is probably the most widespread of all African forest-zone anthropoid primate species. Chimpanzees live in social communities of several dozen animals and can habituate themselves to African rain forests, woodlands, and grasslands. They are generally fruit and plant eaters, but also consume insects, eggs, and meat, including carrion. They have a wide variety of diets that include hundreds of known foods. To date, the species P. troglodytes have been divided into four subspecies, including the Central Chimpanzee P. t. troglodytes, the Eastern Chimpanzee P. t. schweinfurthii, the Nigeria-Cameroon Chimpanzee P. t. vellerosus and the West African Chimpanzee P. t. verus.
Chimpanzee in Biomedical Research
According to the results of the Chimpanzee Genome Project, chimpanzees have high genetic similarity with humans and have the closest common ancestor to humans, so they are widely used in the field of biomedical research. From the perspective of evolution, it is the species closest to humans in existing organisms, and therefore provide new insights into biology and evolution. Moreover, chimpanzees are the only animal models that are sensitive to all five major hepatitis viruses: A, B, C, D and E. Researches of chimpanzees have led to the development of diagnostic tests and vaccines for hepatitis A and hepatitis B. The hepatitis A and hepatitis B vaccines reduced infection rates by 92% and 82%, respectively. Currently, ongoing research with chimpanzees is underway to develop hepatitis C vaccines and antiviral therapies. In addition, chimpanzees are important in the development and testing of monoclonal antibody therapies for autoimmune diseases and cancer, as their cell surface receptors and cytokine profiles are almost identical to humans. Monoclonal antibodies tested in chimpanzees are used to treat B-cell non-Hodgkin's lymphoma and several inflammatory and arthritic conditions, including rheumatoid arthritis, Crohn's disease, ulcerative colitis, and psoriasis. Furthermore, chimpanzees should still be used to complete the development of monoclonal antibodies in the pipeline. Last but not least, some derivatives from chimpanzees, such as stem cells, plasma and body fluids, are also widely used in biological research.
Creative Biolabs offers a large range of high-quality non-human primate bioproducts including whole blood, serum, plasma, primary cells, and body fluids. Biological products for non-human primates at Creative Biolabs come from healthy captive-bred monkeys and diseases models. In addition, we can also offer customized non-human primate products. Please feel free to contact us for more specific needs.