Category:
Non-Human Primate (NHP) related Antibody Products
HLA-DRB1 Monoclonal Antibody (JES15A) (NHP-AB134)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing mouse against activated human peripheral blood mononuclear cells. It is used only in in vitro assays.
Introduction:
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
Conjugate:
None
Antibody Isotype:
IgG2aκ
Applications:
Flow Cytometry; IF; WB
Host Species:
Mouse
Species Reactivity:
Baboon; Chimpanzee; Dog; Human; Monkey
Immunogen:
Activated human peripheral blood mononuclear cells
Purification:
Protein G affinity chromatography
Format:
Liquid
Concentration:
0.2 mg/mL
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Storage:
Store at 4⁰C.
Target:
HLA-DRB1
Clone:
JES15A
Clonality:
Monoclonal
Alternative Names:
Clone P2-beta-3; DR-16; DW2.2/DR2.2; HLA class II histocompatibility antigen, DR-1 beta chain; HLA class II histocompatibility antigen, DRB1-15 beta chain; HLA class II histocompatibility antigen, DRB1-16 beta chain; HLA class II histocompatibility antigen, DRB1-3 chain; human leucocyte antigen DRB1; lymphocyte antigen DRB1; MHC class II antigen; MHC class II antigen DRB1*15; MHC class II antigen DRB1*16; MHC class II antigen DRB1*3; MHC class II HLA-DR beta 1 chain; MHC class II HLA-DR-beta cell surface glycoprotein; MHC class II HLA-DRw10-beta
Entrez Gene ID:
3123
- HLA-DRB1 Monoclonal Antibody (JES15A) (NHP-AB134) Data Sheet: Detailed information. datasheet
There are currently no customer reviews or questions for HLA-DRB1 Monoclonal Antibody (JES15A) (NHP-AB134). Click the button below to contact us or submit your feedback about this product.
Your research is unique, and we understand that standard products may not always fit. Our team of experts specializes in custom NHP sample collections. We can design a tailored protocol to meet your specific research requirements, including samples with unique anticoagulant types, customized volumes, or from specific disease models.
You may also be interested in…
Online Inquiry
For research use only. Not intended for any clinical use.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.