JNK1/JNK2/JNK3 Monoclonal Antibody (UCHT2) (NHP-AB222)

• This product is an antibody that was generated by immunizing mouse against recombinant human MAPK8 protein. It is used only in in vitro assays.

Detailed Product Description

• Introduction: C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8). It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: IF; IP; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Bovine; Dog; Human; Monkey; Mouse; Rat; Zebrafish
• Immunogen: Recombinant human MAPK8 protein

Product Property

• Purification: Affinity purification
• Format: Liquid
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Storage: Store at -20⁰C. Avoid freeze-thaw cycles.

Target Information

• Target: JNK1/JNK2/JNK3
• Clone: UCHT2
• Clonality: Monoclonal
• Alternative Names: c-Jun N-terminal kinase 1; FLJ12099; FLJ33785; JNK-46; JNK1 beta1 protein kinase; JNK3; JNK3A; JUN N-terminal kinase; MAP kinase 8; MAPK 10; MAPK 8; MAPK10; MGC50974; mitogen activated protein kinase 8; Mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; MK10; OTTHUMP00000019552; p493F12; p54 gamma; p54bSAPK; Phospho-JNK; PRKM10; protein kinase JNK1; protein kinase mitogen-activated 8; SAPK gamma; SAPK1c; stress-activated protein kinase 1; Stress-activated protein kinase 1c; Stress-activated protein kinase JNK1
• Entrez Gene ID: 5599/5601/5602