Accelerate Your Drug Discovery Process!

Are you currently facing long drug development cycles, difficulty in predicting human responses to drugs, or challenges in complex disease modeling? Creative Biolabs' NHP-based research models and services help you accelerate drug discovery, provide highly predictive data, and streamline regulatory submissions. We achieve this through our advanced NHP disease models, comprehensive biospecimen resources, and expert bioanalysis platforms.

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Key Advantages

• Genetic and Physiological Similarity to Humans: NHPs share a high degree of genetic and physiological homology with humans (93–95% genetic sharing).
• "Gold Standard" for Translational Studies: They are considered the best model for translating research findings from the lab to human clinical trials.
• Predictive Value: Their similarity to humans makes them an unparalleled model for accurately evaluating drug safety and efficacy.
• Risk Mitigation: Using NHPs helps reduce the risk of unforeseen side effects when new drugs move into human trials.
• Support for Advanced Therapies: They are particularly critical for the development of biologics, vaccines, and advanced therapies.

NHP Species Types

The selection of an appropriate NHP species is paramount to the success of a research project. Each species offers unique characteristics that make it suitable for specific areas of study. Creative Biolabs provides access to a diverse range of NHP species to meet the needs of your specialized research.

Applications in Drug Discovery & Development

The highly predictive nature of NHP models makes them an indispensable tool across the entire R&D lifecycle. Our services support a wide array of applications, from early-stage discovery to late-stage regulatory submissions.

• Toxicology and Safety Assessment: Use NHP models for non-rodent toxicity studies required by global regulatory bodies, ensuring a higher degree of safety and predictability before first-in-human trials.
• Pharmacokinetics/Pharmacodynamics (PK/PD): Gain a detailed understanding of drug-body interactions with data that translates directly to humans, enabling better dose selection and optimizing clinical trial design.
• Disease Modeling: Our advanced NHP models of diseases like inflammatory arthritis or metabolic syndrome provide a more clinically relevant platform for testing new therapies compared to traditional rodent models. This supports cutting-edge therapies in a highly translational manner.
• Biologics and Vaccine Development: Test the efficacy and immunogenicity of novel biologics, monoclonal antibodies, and vaccines in a host that accurately reflects human immune responses, accelerating development timelines.
• Advanced Therapy Evaluation: For gene and cell therapies, NHPs are essential for evaluating biodistribution, long-term efficacy, and potential off-target effects in a system that is the closest possible match to a human.

Available Biologicals

Creative Biolabs offers a comprehensive library of NHP biospecimens, all collected with rigorous quality control to ensure they are compatible with a wide range of downstream analytical applications. Our specimens come with a COA and are processed under strict protocols to maintain their integrity.

NHPs In Vivo Research Services

Creative Biolabs provides a suite of exclusive, NHP-based research services designed to accelerate your drug development program and provide the highly predictive data.

• Toxicology and Safety Studies: Leverage our extensive experience to conduct thorough toxicology studies, including single- and repeat-dose studies. Our NHP models offer a predictive platform for assessing the safety profile of your drug candidates.
• PK/PD: Our expert services offer an in-depth comprehension of a drug’s ADME within a model that accurately reflects human physiological processes. This facilitates the refinement of dosage and formulation strategies.
• Assess Immunogenicity and Immune Response: With their human-like immune systems, NHPs are the optimal model for assessing the immunogenicity of biologics and vaccines. We help you predict potential immune responses and develop strategies to mitigate them.
• Efficacy Evaluation: Creative Biolabs has developed and validated a range of NHP disease models for areas such as infectious diseases, metabolic disorders, and autoimmune conditions. These models enable a deeper understanding of disease pathogenesis and the evaluation of targeted therapies.
• Bioanalysis and Biomarker Discovery: Our expert team conducts comprehensive bioanalysis and assists in the identification of biomarkers for your therapeutic area.

Rigorous Quality & Animal Care

At Creative Biolabs, our commitment to rigorous quality and animal welfare is non-negotiable. Our strict standards not only uphold ethical principles but also guarantee the credibility and reproducibility of your research data.

• Ethical Sourcing: All NHPs are sourced from captive-bred colonies or certified, reputable suppliers who adhere to the highest international ethical standards. We never use wild-caught animals.
• Specific Pathogen-Free (SPF) Status: All Creative Biolabs NHPs are maintained in a controlled, SPF environment to eliminate common pathogens that could compromise animal health and research data. This ensures a clean and consistent research model.
• Professional Veterinary Care and Animal Husbandry: Our dedicated team of veterinarians and animal care technicians provides continuous, high-quality care, including daily health monitoring, enrichment, and nutritional management.
• Comprehensive Quality Control: Every aspect of our NHP program, from breeding and husbandry to sample collection and processing, is subject to a rigorous quality control program to ensure data integrity and reliability.

Contact Us

At Creative Biolabs, we understand that every project is unique, with its own set of challenges and objectives. Our team is committed to a collaborative approach, working closely with you to understand your specific needs and design a research strategy that delivers optimal results. From selecting the most appropriate NHP species and disease model to providing high-quality bio-specimens and advanced bioanalytical support, we are here to guide you every step of the way. Contact us today to discuss your project and discover how Creative Biolabs can help you achieve your research goals.