Non-Human Primate (NHP) In Vivo Experimentation Facilities

Are you currently facing long drug development cycles, supply shortages of NHPs, or challenges in obtaining high-predictability preclinical data? Our NHP In Vivo Experimentation Facilities help you accelerate drug discovery and improve clinical translation through our reliable NHP supply chain and advanced research platforms. We provide a single-source solution for comprehensive care, sophisticated experimental procedures, and data analysis to de-risk your pipeline and streamline the path to IND submission.

Advanced Imaging Platforms for Translational NHP Studies

Enabling biodistribution tracking and real-time monitoring in primate models to improve translational relevance.

Overview of Our Platform

What Are Our Platforms?

Our NHP In Vivo Experimentation Facilities provide a comprehensive suite of services that leverage the high translational value of nonhuman primates in preclinical research. With their close genetic, physiological, and anatomical similarities to humans, NHPs are an indispensable model for certain types of studies where other models, like rodents, fall short. We offer a holistic solution, from ethical sourcing and housing to sophisticated study design and data analysis, ensuring a seamless and efficient research process for our clients.

Our platforms are designed to support a wide range of critical research applications, including:

Preclinical Drug Safety and Efficacy Studies: We provide a reliable model for testing the safety and efficacy of novel therapeutic candidates, including biologics, small molecules, and vaccines, before they advance to human clinical trials.
Regenerative Medicine and Cell Therapy: Our facilities enable the assessment of cell and tissue viability, engraftment, and long-term functional outcomes of regenerative therapies in a highly relevant model.
Infectious Disease and Vaccine Research: We support the development and evaluation of vaccines and antiviral therapies for infectious diseases, allowing for accurate modeling of immune responses and viral pathogenesis.

Why Choose Our Platforms?

Navigating the complexities of NHP research can present significant challenges, including recent supply chain disruptions that have delayed critical research projects. Creative Biolabs addresses these pain points by offering a stable and reliable supply of high-quality NHPs, sourced from our extensive global network. This ensures project continuity and rapid initiation, a crucial factor in accelerating your drug discovery timeline.

Our scientific team, with decades of collective experience, provides the expertise needed to design, execute, and interpret complex NHP studies with precision. By providing a single-source solution for everything from animal care to advanced data analysis, we eliminate the logistical burdens of managing multiple vendors. This allows our clients to focus on the science, confident that their results are highly predictive of human outcomes and will stand up to the scrutiny of regulatory bodies, ultimately increasing the probability of a successful IND submission.

Containment system for group housing of macaques. (OA Literature) Fig.1 Housing containment system for group accommodation of macaques.¹

Key Benefits of Our Platforms

Accelerated project initiation and timelines. Our streamlined protocols and robust sourcing network enable rapid study startup, significantly reducing lead times for time-sensitive projects.
Data with high predictability of human outcomes. NHPs' close physiological and genetic resemblance to humans ensures highly translatable data, de-risking the transition to clinical trials and improving the likelihood of a successful outcome.
Extensive expertise in multiple therapeutic areas. Our team of scientists and veterinarians offers deep domain knowledge across a range of therapeutic areas, providing insightful study design and data interpretation tailored to your specific research goals.
Robust and consistent NHP supply chain. We maintain a stable and consistent supply of healthy, well-characterized NHPs. Our ethical sourcing and strong global breeding network relationships mitigate supply disruptions, ensuring your research proceeds without delay.

Core Capabilities of Our Platforms

Comprehensive NHP Care & Health Monitoring: Our facilities are accredited and equipped with state-of-the-art systems for constant health monitoring and care, adhering to the highest standards of animal welfare.
High-Containment Research Support: We provide secure facilities that are specifically designed for safe and compliant research involving infectious agents and other biohazards.
Surgical & Catheterization Suites: Our surgical suites are fully equipped for complex surgical procedures, allowing for the precise implantation of telemetry devices or the establishment of specialized models.
Telemetry & Behavioral Monitoring Rooms: We offer real-time, continuous monitoring of physiological parameters such as ECG and blood pressure, as well as objective observation of behavioral changes.
Longitudinal Study Housing: Our specialized housing systems are designed to support long-term studies, ensuring animal well-being while enabling continuous data collection over months or years.

Applications Enabled

Evaluation of gene therapy biodistribution and expression.
Immunology assays with NHP primary cells to assess immune responses.
Modeling of age-related diseases and therapeutic interventions.

Deliverables

Processed datasets and raw data files (e.g., physiological data, biomarker panels).
Detailed study report with all raw data, analysis, and QC logs.
QC logs & metadata (species, donor information, health status).
Statistical analysis summary and interpretation.
High-resolution imaging files (e.g., MRI, CT).

Frequently Asked Questions

Q: What is the turnaround time for a standard NHP study?

A: Our extensive NHP colony and streamlined project initiation process allow us to begin studies rapidly. Once a protocol is finalized, we can often begin in-life studies within a few weeks, depending on the complexity of your project. For more specific timelines, we encourage you to Contact Our Team for More Information.

Q: How do you ensure the ethical sourcing and well-being of the primates?

A: Animal welfare is our highest priority. All of our NHPs are ethically sourced from reputable, audited breeding facilities, and our animal care program is managed by experienced veterinarians and staff who prioritize enrichment and psychological well-being.

Q: What are the key advantages of using NHP models over other animal models like rodents?

A: NHP models offer a higher degree of translational relevance due to their close genetic and physiological similarity to humans. This is especially critical for studies involving complex diseases, neurosciences, or biologics, where data from other models may not be as predictive of clinical outcomes. Our team can help you determine if an NHP model is the right fit for your research.

Q: Can you support custom study designs for unique research applications?

A: Absolutely. Our scientific team specializes in designing and executing custom protocols tailored to your specific research needs. We work collaboratively with our clients from the initial consultation to develop a robust study design that addresses your unique scientific questions and goals.

Q: What kind of data will I receive at the end of the study?

A: Our deliverables are comprehensive and designed to support regulatory submissions. You will receive a complete study report, raw data files in a client-friendly format, statistical analysis summaries, and detailed QC logs. We provide full data transparency to ensure you have everything you need for your downstream analysis.

Contact Us

At Creative Biolabs, our NHP In Vivo Experimentation Facilities provide a powerful, reliable, and ethical solution for your most challenging preclinical research needs. Our commitment to scientific excellence, animal welfare, and client partnership ensures you get the high-quality, translatable data required to advance your pipeline. Ready to leverage our NHP In Vivo Experimentation Facilities for your next study? Contact our expert team today to discuss how we can help you accelerate your research and achieve your goals.

Reference

Prescott, Mark J., et al. "Opportunities for refinement of non-human primate vaccine studies." Vaccines 9.3 (2021): 284. Distributed under Open Access license CC BY 4.0, without modification. DOI: https://doi.org/10.3390/vaccines9030284