Category:
Non-Human Primate (NHP) related Antibody Products
PSMA6 Polyclonal Antibody (NHP-AB433)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PSMA6 (NP_002782.1). It is used only in in vitro assays.
Introduction:
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome.
Conjugate:
None
Antibody Isotype:
IgG
Applications:
IF; IHC; WB
Host Species:
Rabbit
Species Reactivity:
Human; Monkey; Mouse; Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PSMA6 (NP_002782.1)
Purification:
Affinity purification
Format:
Liquid
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage:
Store at -20⁰C. Avoid freeze-thaw cycles.
Clonality:
Polyclonal
Alternative Names:
27 kDa prosomal protein; Macropain iota chain; macropain subunit iota; MGC22756; MGC2333; MGC23846; Multicatalytic endopeptidase complex iota chain; PROS 27; PROS-27; prosomal P27K protein; proteasome (prosome, macropain) subunit, alpha type, 6; proteasome alpha 6 subunit; Proteasome iota chain; Proteasome subunit alpha type-6; proteasome subunit iota; PSA6; PSMA 6; testicular secretory protein Li 44
Entrez Gene ID:
5687
Function:
An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
- PSMA6 Polyclonal Antibody (NHP-AB433) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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