Rabbit Anti-TAAR1 Polyclonal Antibody (NHP-AB286)

• This product is an antibody that was generated by immunizing rabbit against a portion of amino acids 225-250 of human TAAR1. It is used only in in vitro assays.

Detailed Product Description

• Introduction: TA1 has been reported in human brain, dorsal root ganglion, olfactory bulb, kidney, liver, lung, pancreas, prostate, skeletal muscle, small intestine, spleen, spinal cord, and stomach. An EST for TA1 has been identified from a human stomach cancer library. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This turn-off activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates.
• Conjugate: None
• Applications: IHC; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Chimpanzee; Human; Monkey; Rat
• Immunogen: A portion of amino acids 225-250 of human TAAR1

Product Property

• Purification: Protein G Column
• Format: Liquid
• Concentration: 1 mg/mL
• Buffer: PBS, 0.05% BSA, 0.05% sodium azide.
• Storage: Short term: 4˚C. Long term: Store at -20˚C. Avoid freeze-thaw cycles.

Target Information

• Clonality: Polyclonal
• Alternative Names: MGC126874; MGC138399; RP11-295F4.9; RTAR1; Snorf33; TaR-1; trace amine receptor 1; Trace amine-associated receptor 1
• Entrez Gene ID: 134864