SPR Polyclonal Antibody (NHP-AB466)

• This product is an antibody that was generated by immunizing rabbit against a synthetic peptide of human SPR. It is used only in in vitro assays.

Detailed Product Description

• Introduction: SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: IHC; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Human; Monkey; Mouse; Rat
• Immunogen: A synthetic peptide of human SPR

Product Property

• Purification: Affinity purification
• Format: Liquid
• Concentration: 0.5 mg/mL
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Storage: Store at -20⁰C. Avoid freez-thaw cycles.

Target Information

• Clonality: Polyclonal
• Alternative Names: Sepiapterin reductase; short chain dehydrogenase/reductase family 38C, member 1; SPR
• Entrez Gene ID: 6697