TIMP2 Monoclonal Antibody (KIP1/769) (NHP-AB224)

• This product is an antibody that was generated by immunizing mouse against a ovalbumin - conjugated synthetic peptide of Metalloproteinase Inhibitor 2 (Human). It is used only in in vitro assays.

Detailed Product Description

• Introduction: TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
• Conjugate: None
• Antibody Isotype: IgG2a
• Applications: ELISA; IHC-P; WB

Technical Specifications

• Host Species: Mouse
• Species Reactivity: Bovine; Chicken; Dog; Gibbon; Gorilla; Guinea Pig; Hamster; Horse; Human; Monkey; Mouse; Pig; Rabbit; Rat; Sheep; Zebrafish
• Immunogen: A ovalbumin - conjugated synthetic peptide of Metalloproteinase Inhibitor 2 (Human)

Product Property

• Purification: Affinity Chromatography
• Format: Liquid
• Concentration: 0.5 mg/mL
• Buffer: Phosphate-buffered solution, pH 7.2, 0.09% sodium azide at 0.5 mg/ml.
• Storage: Store at 4⁰C. Avoid freezing.

Target Information

• Clone: KIP1/769
• Clonality: Monoclonal
• Alternative Names: CSC-21K; Metalloproteinase inhibitor 2; testicular secretory protein Li 57; TIMP 2; TIMP-2; tissue inhibitor of metalloproteinase 2; tissue inhibitor of metalloproteinase-2; Tissue inhibitor of metalloproteinases 2
• Entrez Gene ID: 7077