Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
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HighlightsVoltage-dependent potassium channels (Kv channels) are crucial for the electrical signaling in neurons. Potassium voltage-gated channel subfamily C, also known as Kv3 channels, belongs to the family of the voltage-dependent potassium channels. One feature that distinguishes these channels from those in the 11 other mammalian Kv families, (Kv1-Kv2 and Kv4-Kv12) is that they typically open only at positive potentials and that both activation and deactivation in response to rapid changes of voltage. There are four channels in the Kv3 family: Kv3.1, Kv3.2, Kv3.3, and Kv3.4. Studies have shown that each channel in the Kv3 family exists in multiple isoforms generated through alternative mRNA splicing. In addition, Kv3.3 and Kv3.4 channels differ from Kv3.1 and Kv3.2 channels in having an NH2-terminal ball structure that causes rapid channel inactivation with sustained depolarization. Most importantly, Kv3 channels can regulate rapid spiking, transmitter release and dendritic integration of many central neurons.
Here, we have described in details of members of the VGKC subfamily C, which including but not limited to potassium voltage-gated channel subfamily C member 1, potassium voltage-gated channel subfamily C member 2, and potassium voltage-gated channel subfamily C member 3. To learn more detailed information, please click the links below.
Based on our advanced Magic™ membrane protein production platform, Creative Biolabs is committed to offering various target membrane protein products in required formats using various strategies, such as detergent micelles, proteoliposomes, nanodiscs, lipoparticles, polymers, stable cell line.
Furthermore, our Magic™ membrane protein antibody discovery platform can help to discover antibodies against these targets, even fully humanized antibodies, by various approaches such as hybridoma technology, phage display technology. We also present DNA immunization service for anti-membrane protein antibody development. To get more detailed information, please feel free to contact us.
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