Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsVoltage-gated potassium (Kv) channels are quintessential regulators of electrical excitability in the nervous system. Potassium voltage-gated channel subfamily D (Kv4 channels) is a member of the Kv channels that are highly expressed in the brain, heart, and smooth muscles. Currently, there are three subtypes of the Kv4 channels have been determined, namely Kv4.1, Kv4.2, and Kv4.3. They are highly homologous within the transmembrane regions, with divergent amino and carboxy termini. Studies have shown that Kv4 channels are important components of the IKA in the nervous system and contribute to the Ito current in cardiac myocytes, where they help to repolarize the early phase of the action potential. What’s more, depending on the frequency of repetitive spike firing, Kv4 channels can also regulate the interspike interval (slow repetitive firing) and the duration of the action potential (fast repetitive firing) in CNS neurons.
Here, we have described in details of members of the VGKC subfamily D, including potassium voltage-gated channel subfamily D member 1, potassium voltage-gated channel subfamily D member 2, and potassium voltage-gated channel subfamily D member 3. To learn more detailed information, please click the links below.
With the help of our advanced MemDX™ membrane protein production platform, Creative Biolabs is committed to offering various target membrane protein products in required formats using various strategies, such as detergent micelles, proteoliposomes, nanodiscs, MP-VLPs, polymers, stable cell line.
In addition, our MemDX™ membrane protein antibody discovery platform can help to discover antibodies against these targets, even fully humanized antibodies, by various approaches such as hybridoma technology, phage display technology. We also present DNA immunization service for anti-membrane protein antibody development. If you are interested in the service we can provide, please feel free to contact us and get more information.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
