Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsVoltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Potassium voltage-gated channel subfamily E (Kv5 channels) is composed of membrane-spanning proteins that interact with ion channels and modify their properties. Their structure consists of a single membrane-spanning α helix, and extra- and intracellular N and C termini, respectively. To date, five human genes have been identified and denoted KCNE1-5. They cannot generate current themselves, but they have the ability to alter the behavior and facilitate the native functions of certain ion channels. Studies have shown that different KCNE isoforms are widely and differentially expressed in muscular and neuronal tissues as well as in epithelial cells. What’s more, it has been proved that mutations in KCNE genes could lead to disruptions of diverse physiological systems and diseases such as cardiac arrhythmias, deafness, and paralysis.
Here, we have described in detail of members of the VGKC subfamily E, which including but not limited to potassium voltage-gated channel subfamily E member 1, potassium voltage-gated channel subfamily E member 2, potassium voltage-gated channel subfamily E member 3 and potassium voltage-gated channel subfamily E member 4. To learn more detailed information, please click the links below.
Based on our advanced MemDX™ membrane protein production platform, Creative Biolabs is committed to offering various target membrane protein products in required formats using various strategies, such as detergent micelles, proteoliposomes, nanodiscs, MP-VLPs, polymers, stable cell line.
Furthermore, our MemDX™ membrane protein antibody discovery platform can help to discover antibodies against these targets, even fully humanized antibodies, by various approaches such as hybridoma technology, phage display technology. We also present DNA immunization service for anti-membrane protein antibody development. To get more detailed information, please feel free to contact us.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
