Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsPotassium voltage-gated channel subfamily KQT, also known as KQT-like channels (KCNQ channels), are members of a family of voltage-dependent potassium-selective channels that are involved in the control of cellular excitability. They possess no tetramerization domain which differs from voltage-gated 6TM helix channels. Consequently, they rely on interaction with accessory subunits or form heterotetramers with other members of the family. Currently, 5 members of the KCNQ family have been identified. It has been reported that the expression of KCNQ proteins has been found in diverse tissues, such as heart, brain, pancreas, lung, placenta, and ear. Remarkably, mutations in four of the five known members of this family have been associated with different hereditary human disorders. While mutations in the KCNQ1 subunit (KvQT1) lead to arrhythmia in the human long QT syndrome, mutations in KCNQ2 or KCNQ3 are associated with a benign form of epilepsy. It has also been shown that KCNQ4 is mutated in a dominant form of progressive hearing loss.
Here, we have described in detail of members of the KCNQ protein family, which includes but not limited to potassium voltage-gated channel subfamily KQT member 1, potassium voltage-gated channel subfamily KQT member 2, and potassium voltage-gated channel subfamily KQT member 3. To learn more detailed information, please click the links below.
Based on advanced Magic™ membrane protein production platform, Creative Biolabs is confident in offering various target membrane protein products in required formats using various strategies, such as detergent micelles, proteoliposomes, nanodiscs, lipoparticles, polymers, stable cell line.
Furthermore, our Magic™ membrane protein antibody discovery platform can help to discover antibodies against these targets, even fully humanized antibodies, by various approaches such as hybridoma technology, phage display technology. Besides, we also present DNA immunization service for anti-membrane protein antibody development. Please feel free to contact us for more information.
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