Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsProtease-activated receptors (PARs) are a subfamily of related G protein-coupled receptors that are activated by cleavage of part of their extracellular domain. Until now, four members (PAR1-4) of the PARs family have been determined and each is expressed at significant levels throughout the body. Particularly, PARs are highly expressed in platelets, and also on endothelial cells, myocytes and neurons. Studies have shown that PARs represent a component of the innate inflammatory response and are involved in diverse physiological processes, such as neutrophil recruitment, increased perfusion, pain, and swelling. Also, it is believed that PARs can act as a first “alarm system” for bacterial invasions as they are present in periodontal epithelial cells and are capable of recognizing and responding to bacterial infections. Moreover, endothelial PARs participate in the regulation of vascular tone and permeability while in vascular smooth muscle they mediate contraction, proliferation, and hypertrophy.
Here, we give a comprehensive introduction to members of the PARs family, including but not limited to proteinase-activated receptor 1, proteinase-activated receptor 2. To learn more detailed information, please click the links below.
Aided by our advanced MemDX™ membrane protein production platform, Creative Biolabs is confident in offering diverse target membrane protein products in required formats using various strategies, such as detergent micelles, proteoliposomes, nanodiscs, MP-VLPs, polymers, stable cell line.
Meanwhile, our MemDX™ membrane protein antibody discovery platform can help to discover antibodies against these targets, even fully humanized antibodies, by various approaches such as hybridoma technology, phage display technology. We also present DNA immunization service for anti-membrane protein antibody development. To get more detailed information, please feel free to contact us.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
