Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | Prostaglandin D2 receptor |
| Gene Name | PTGDR |
| Uniprot | Q13258 (Human); P70263 (Mouse) |
| Synonym | DP; AS1; DP1; ASRT1; PTGDR1; prostaglandin D2 receptor; PGD2 receptor; PTGDR; Prostaglandin D2 receptor |
| Background | PTGDR is encoded by the PTGDR gene. It belongs to the G-protein-coupled receptor (GPCR) family which provides targets for about 34% of the marketed drugs and account for a global sales volume of over 180 billion US dollars annually. It belongs to prostanoid receptors and cloned based on their high amino acid and cDNA sequence homologies with other GPCRs. PTGDR possess seven transmembrane alpha helices and uses PGD2 as the preferred endogenous ligand, which is a major metabolic product of cyclo-oxygenase (COX)-1 and released after IgE-mediated mast cell activation. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX70 | NativeExtract™ Human PTGDR Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| MPX3445K | MemDX™ Membrane Protein Human PTGDR (Prostaglandin D2 receptor) Expressed in vitro E.coli expression system, Full Length | E.colicell-free | Full length | Detergent |
| MP1051X | MemDX™ Membrane Protein Human PTGDR (Prostaglandin D2 receptor) for Antibody Discovery | Wheat germ cell-free | Full length | N/A |
| Please for more products or customization | ||||
R**y: The quality of the proteins is excellent.
24/ Apr/2023
F***ey: The shipping was very fast.
10/ Dec/2023
We provide tailored solutions to meet your specific requirements. Please for more services.
Creative Biolabs offers siRNA production services for gene silencing. Therapeutic efficacy, however, hinges not merely on intracellular siRNA transport but also on sustained mRNA knockdown without eliciting innate immune responses—a balance that current nanoparticle formulations strive to achieve through modular design. It is plausible that iterative refinements in carrier biocompatibility and targeting specificity will further potentiate RNAi’s applicability across diverse pathologies, from oncology to neurodegenerative disorders.
Creative Biolabs offers ex vivo and in vivo gene delivery services. In gene therapy, therapeutic strategies centered around PTGDR can be generally classified into two main approaches: administering vectors directly into the host tissues in vivo, or performing ex vivo genetic modification on autologous cell groups before their adoptive transfer back into the body. The in vivo methods often utilize recombinant AAV vectors. These vectors show significant affinity for various cell types and tissues, thus facilitating widespread gene delivery throughout the body. Compared with other viral systems, AAV vectors trigger a lower immune response. Clinical investigations indicate that AAV serotypes can be modified to enhance gene transfer efficiency in organs like the lungs or skin.
Creative Biolabs offers comprehensive and innovative services to drive the development of PTGDR cell therapy. Please for more services.
Creative Biolabs offers gene editing services for PTGDR-targeted cells. Gene editing technology can modify the PTGDR gene in target cells, either by knocking out the receptor to study its function or by introducing specific mutations to enhance or inhibit its activity. After editing, the cells are analyzed to confirm the successful modification of the PTGDR gene. Techniques like PCR, sequencing, and functional assays are used to verify the genetic changes and their effects on cell behavior.
Creative Biolabs offers development services for PTGDR-targeted cell therapy products. The modified cells are tested in vitro and in vivo to evaluate their safety and efficacy. Animal models of relevant diseases are used to assess the therapeutic potential of the cell therapy products. If preclinical testing shows promising results, the cell therapy products can proceed to clinical trials. These trials involve multiple phases to evaluate the safety, dosage, and efficacy of the therapy in human patients.
Creative Biolabs offers development and preclinical research services for targeting PTGDR in immune cell therapy. PTGDR is expressed in various immune cells, including T cells, dendritic cells, and macrophages. Targeting PTGDR in these cells can modulate immune responses and has potential applications in immunotherapy.
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All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
