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PTGER1 Membrane Protein Introduction

Introduction Related Products Customer Reviews Customized Production Drug Discovery

Introduction of PTGER1

Protein Name Prostaglandin E receptor 1
Gene Name PTGER1
Uniprot P34995 (Human); P35375 (Mouse)
Synonym EP1; prostaglandin E2 receptor EP1 subtype; PGE receptor, EP1 subtype; PGE2 receptor EP1 subtype; prostaglandin E receptor 1 (subtype EP1), 42kD; prostaglandin E receptor 1 (subtype EP1), 42kDa; prostaglandin E receptor 1, subtype EP1; prostanoid EP1 receptor
Background PTGER1, also known as Prostaglandin E2 receptor 1 (EP1), is a 42 kDa prostaglandin receptor encoded by the PTGER1 gene. Animal model studies have implicated EP1 in various physiological and pathological responses. However, key differences in the distribution of EP1 between these test animals and humans as well as other complicating issues make it difficult to establish the function(s) of this receptor in human health and disease.

PTGER1 Related Products

Membrane Protein Products

Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.

CAT# Product Name Expression System Protein Length Solubilizing Agents
S01YF-1023-KX69 NativeExtract™ Human PTGER1 Membrane Protein (Full length, Super Nanodisc) HEK293 cells Full length Native Nanodisc
MPX3535K MemDX™ Membrane Protein Human PTGER1 (Prostaglandin E receptor 1) Expressed in vitro E.coli expression system, Full Length E.colicell-free Full length Detergent
MP1053X MemDX™ Membrane Protein Human PTGER1 (Prostaglandin E receptor 1) for Antibody Discovery Wheat germ cell -free Full length N/A
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Customer Reviews

H***ony: The team at Creative Biolabs was very professional and responsive throughout the entire process. They provided detailed information about the protein and even offered guidance on how to handle and store it properly.

27/ Jan/2024

S***et: The PTGER1 Protein has been performing exceptionally well in my experiments, and I have already seen promising results. I highly recommend Creative Biolabs for anyone looking for high-quality proteins and outstanding customer support.

12/ Jun/2024

Customized Membrane Protein Production

Different membrane protein formats (Creative Biolabs Original)

PTGER1 Drug Discovery and Development

PTGER1 Small Molecule Drug Development

Small molecule drug development services (Creative Biolabs Original)

Anti-PTGER1 Antibody Discovery

Processes of antibody discovery (Creative Biolabs Original)

PTGER1 Gene Therapy Development

We provide tailored solutions to meet your specific requirements. Please inquire us for more services.

Gene Delivery Viral Vectors

Creative Biolabs offers gene delivery research services using viral vectors. Within the specific context of gene therapy strategies targeting Prostaglandin E Receptor 1 (PTGER1), AAVs can be strategically engineered. Such modifications enable the packaging and delivery of a functional PTGER1 gene sequence. Retroviral vectors demonstrate proficiency in transducing actively dividing cells. Lentiviruses, in contrast, possess the capacity to infect both dividing and non-dividing, post-mitotic cells. While both vector types present the potential benefit of stable, long-term gene expression resultant from integration into the host genome, this very mechanism carries an inherent risk: insertional mutagenesis. This potential hazard mandates exceptionally careful vector design principles and necessitates rigorous, comprehensive pre-clinical safety assessments before translation towards clinical investigation.

Gene Delivery Non-Viral Vectors

Creative Biolabs offers gene delivery research services using non-viral vectors. LNPs can encapsulate nucleic acids encoding PTGER1. They are less immunogenic than some viral vectors and can be designed to target specific cell types by modifying the lipid composition or attaching targeting ligands. LNPs have shown promise in delivering mRNA encoding PTGER1, enabling transient gene expression, which can be beneficial in cases where short-term correction of PTGER1 function is sufficient or to avoid potential risks associated with permanent gene integration.

PTGER1 Cell Therapy Discovery

Creative Biolabs offers comprehensive and innovative services to drive the development of PTGER1 cell therapy. Please inquire with us for more services.

Functional Assays to Assess PTGER1-Modified Cells

Creative Biolabs offers functional assay services to assess PTGER1-modified cells. Assess the viability and growth of PTGER1-engineered cells by means of assays such as the MTT assay, BrdU uptake measurement, or flow cytometry-based examination of the cell cycle.

Biomarker Development for PTGER1 Cell Therapy

Creative Biolabs offers biomarker development services for PTGER1 cell therapy. Identify and validate peripheral blood biomarkers that correlate with the presence and activity of PTGER1-modified cells. This can aid in monitoring treatment response and patient selection. Utilize transcriptomics, proteomics, and metabolomics to identify biomarkers and pathways affected by PTGER1 cell therapy. This comprehensive approach can provide insights into the mechanisms of action and potential off-target effects.

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All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

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