| Protein Name | Prostaglandin E receptor 1 |
| Gene Name | PTGER1 |
| Uniprot | P34995 (Human); P35375 (Mouse) |
| Synonym | EP1; prostaglandin E2 receptor EP1 subtype; PGE receptor, EP1 subtype; PGE2 receptor EP1 subtype; prostaglandin E receptor 1 (subtype EP1), 42kD; prostaglandin E receptor 1 (subtype EP1), 42kDa; prostaglandin E receptor 1, subtype EP1; prostanoid EP1 receptor |
| Background | PTGER1, also known as Prostaglandin E2 receptor 1 (EP1), is a 42 kDa prostaglandin receptor encoded by the PTGER1 gene. Animal model studies have implicated EP1 in various physiological and pathological responses. However, key differences in the distribution of EP1 between these test animals and humans as well as other complicating issues make it difficult to establish the function(s) of this receptor in human health and disease. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX69 | NativeExtract™ Human PTGER1 Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| MPX3535K | MemDX™ Membrane Protein Human PTGER1 (Prostaglandin E receptor 1) Expressed in vitro E.coli expression system, Full Length | E.colicell-free | Full length | Detergent |
| MP1053X | MemDX™ Membrane Protein Human PTGER1 (Prostaglandin E receptor 1) for Antibody Discovery | Wheat germ cell -free | Full length | N/A |
| Please for more products or customization | ||||
H***ony: The team at Creative Biolabs was very professional and responsive throughout the entire process. They provided detailed information about the protein and even offered guidance on how to handle and store it properly.
27/ Jan/2024
S***et: The PTGER1 Protein has been performing exceptionally well in my experiments, and I have already seen promising results. I highly recommend Creative Biolabs for anyone looking for high-quality proteins and outstanding customer support.
12/ Jun/2024
We provide tailored solutions to meet your specific requirements. Please for more services.
Creative Biolabs offers gene delivery research services using viral vectors. Within the specific context of gene therapy strategies targeting Prostaglandin E Receptor 1 (PTGER1), AAVs can be strategically engineered. Such modifications enable the packaging and delivery of a functional PTGER1 gene sequence. Retroviral vectors demonstrate proficiency in transducing actively dividing cells. Lentiviruses, in contrast, possess the capacity to infect both dividing and non-dividing, post-mitotic cells. While both vector types present the potential benefit of stable, long-term gene expression resultant from integration into the host genome, this very mechanism carries an inherent risk: insertional mutagenesis. This potential hazard mandates exceptionally careful vector design principles and necessitates rigorous, comprehensive pre-clinical safety assessments before translation towards clinical investigation.
Creative Biolabs offers gene delivery research services using non-viral vectors. LNPs can encapsulate nucleic acids encoding PTGER1. They are less immunogenic than some viral vectors and can be designed to target specific cell types by modifying the lipid composition or attaching targeting ligands. LNPs have shown promise in delivering mRNA encoding PTGER1, enabling transient gene expression, which can be beneficial in cases where short-term correction of PTGER1 function is sufficient or to avoid potential risks associated with permanent gene integration.
Creative Biolabs offers comprehensive and innovative services to drive the development of PTGER1 cell therapy. Please for more services.
Creative Biolabs offers functional assay services to assess PTGER1-modified cells. Assess the viability and growth of PTGER1-engineered cells by means of assays such as the MTT assay, BrdU uptake measurement, or flow cytometry-based examination of the cell cycle.
Creative Biolabs offers biomarker development services for PTGER1 cell therapy. Identify and validate peripheral blood biomarkers that correlate with the presence and activity of PTGER1-modified cells. This can aid in monitoring treatment response and patient selection. Utilize transcriptomics, proteomics, and metabolomics to identify biomarkers and pathways affected by PTGER1 cell therapy. This comprehensive approach can provide insights into the mechanisms of action and potential off-target effects.
Please feel free to for more information.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.