Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | Prostaglandin E receptor 2 |
| Gene Name | PTGER2 |
| Uniprot | P43116 (Human); Q62053 (Mouse) |
| Synonym | EP2; prostaglandin E2 receptor EP2 subtype; PGE receptor EP2 subtype; PGE2 receptor EP2 subtype; prostaglandin E receptor 2 (subtype EP2), 53kD; prostaglandin E receptor 2 (subtype EP2), 53kDa; prostanoid EP2 receptor |
| Background | PTGER2, also known as EP2 or Prostaglandin E2 receptor 2, is a 53 kDa prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER2. It belongs to the group of four recognized EP receptors, with the remaining ones being EP1, EP3, and EP4. The PTGER2 gene is situated on human chromosome 14 at the p22.1 locus. It consists of 2 introns and 3 exons and encodes a G protein-coupled receptor (GPCR) within the rhodopsin-like receptor family, specifically Subfamily A14. PTGER2 is broadly distributed in humans. It is expressed in the human small intestine, lung, uterus, thymus, brain, cerebral cortex, corneal epithelium, and so on. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX398 | NativeExtract™ Human PTGER2 Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| MPX3444K | MemDX™ Membrane Protein Human PTGER2 (Prostaglandin E receptor 2) Expressed in vitro E.coli expression system, Full Length | E.colicell-free | Full length | Detergent |
| MP1055X | MemDX™ Membrane Protein Human PTGER2 (Prostaglandin E receptor 2) with N-GST tag for Antibody Discovery | Wheat germ cell -free | Full length | N/A |
| MP1054X | MemDX™ Membrane Protein Human PTGER2 (Prostaglandin E receptor 2) without tag for Antibody Discovery | Wheat germ cell -free | Full length | Liposome |
| S01YF-0423-KX546 | MemDX™ Membrane Protein Human PTGER2 (1-23aa) Expressed in HEK293, C-Human Fc tag | HEK293 cells | Partial | N/A |
| Please for more products or customization | ||||
C****ta: I purchased the PTGER2 Protein from Creative Biolabs for my research project, and I couldn't be happier with the results. The protein is of exceptional quality and has been performing very well in my experiments.
03/ Nov/2023
Ch****lle: They were very responsive and provided detailed information about the product. They even offered to help with any issues I might encounter during my research. I highly recommend Creative Biolabs for anyone in need of high-quality proteins and reliable service.
17/ Mar/2024
We provide tailored solutions to meet your specific requirements. Please for more services.
Creative Biolabs offers PTGER2 pathway research services. The PTGER2 assumes a critical role within numerous physiological processes and pathological mechanisms. Regulating this receptor's function could perhaps yield significant clinical advantages in managing a spectrum of challenging conditions. These include chronic pain syndromes, diverse inflammatory ailments, and specific types of malignancies. Therefore, gene therapy strategies represent a pertinent approach; such modalities may be employed to either augment or diminish PTGER2 expression levels. The choice between upregulation and downregulation is necessarily contingent upon the specific therapeutic objective sought for a given pathological context.
Creative Biolabs offers gene editing services. Utilize gene editing techniques to precisely edit the PTGER2 gene in target cells. This can be used to knock out PTGER2 in cancer cells or to introduce specific mutations that alter its function. The gene-editing tools can also be used to modify the PTGER2 gene. They offer high specificity and can be tailored to target specific regions of the gene.
Creative Biolabs offers RNA interference services. Develop siRNA molecules that specifically target PTGER2 mRNA for degradation. This approach can be used to reduce PTGER2 expression in target cells. shRNA can be delivered using viral vectors to continuously produce siRNA in cells, leading to sustained knockdown of PTGER2.
Creative Biolabs offers comprehensive and innovative services to drive the development of PTGER2 cell therapy. Please for more services.
Creative Biolabs offers in vitro and in vivo testing services. The functional consequences of PTGER2 modification in engineered cells necessitate thorough investigation, beginning with in vitro characterization. The PTGER2-modified cells are incubated directly with relevant target cell populations–potentially neoplastic cells or specific immune cell subsets, depending on the therapeutic context. Such investigations are designed to rigorously evaluate both the safety profile and the therapeutic efficacy of the proposed PTGER2-based cellular therapy. Key parameters requiring systematic monitoring within these in vivo settings include the engraftment efficiency of the administered modified cells, their subsequent long-term persistence or survival, and, crucially, the ultimate demonstration of tangible therapeutic effects within the complex biological environment of the living organism.
Creative Biolabs offers development and preclinical research services in combination therapies. Combine PTGER2 cell therapy with other treatments, such as chemotherapy, immunotherapy, or targeted therapies. Evaluate the synergistic effects on disease progression and patient outcomes. Develop sequential treatment protocols where PTGER2 cell therapy is administered before or after other treatments. This can optimize therapeutic efficacy and minimize adverse effects.
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All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
