Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | Prostaglandin F receptor |
| Gene Name | PTGFR |
| Uniprot | P43088 (Human); P43117 (Mouse) |
| Synonym | FP; prostaglandin F2-alpha receptor; FP prostanoid receptor; PGF receptor; PGF2 alpha receptor; prostaglandin receptor (2-alpha); prostanoid FP receptor |
| Background | PTGFR, also known as Prostaglandin F receptor (FP), is a receptor belonging to the prostaglandin (PG) group of receptors. PTGFR binds to and mediates the biological actions of Prostaglandin F2α (PGF2α). It is encoded by the PTGFR gene in humans. PTGFR is expressed as two alternatively spliced transcript variants encoding different isoforms, FPA and FPB, which have different C-terminal lengths. In certain cells, activation of PTGFR also stimulates G12/G13-Gβγ G proteins to activate the Rho family of GTPases signaling proteins and Gi-Gβγ G proteins to activate Raf/MEK/mitogen-activated kinase pathways. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX67 | NativeExtract™ Human PTGFR Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| MPX3450K | MemDX™ Membrane Protein Human PTGFR (Prostaglandin F receptor) Expressed in vitro E.coli expression system, Full Length | E.colicell-free | Full length | Detergent |
| MP1060X | MemDX™ Membrane Protein Human PTGFR (Prostaglandin F receptor) for Antibody Discovery | Wheat germ cell -free | Full length | N/A |
| Please for more products or customization | ||||
E***n: The quality of the PTGFR protein I received is truly top - notch. It arrived in excellent condition, properly packaged to ensure stability during shipping. The purity and functionality of the protein were evident in my subsequent experiments. The data I obtained using this PTGFR protein was consistent and reliable, significantly advancing my research progress.
17/ Aug/2023
A***y: The delivery was timely. Despite some logistical challenges that can occur in international shipping, Creative Biolabs managed to get the PTGFR protein to me within the promised timeframe. This reliability is crucial in the fast - paced world of scientific research.
03/ Oct/2023
We provide tailored solutions to meet your specific requirements. Please for more services.
Creative Biolabs offers ligand-mediated PTGFR production services. Conjugating the vector with ligands that bind specifically to receptors on target cells can enhance the specificity of PTGFR gene delivery. For example, using antibodies or peptides that recognize cell surface markers on specific tissues can direct the vector to those cells. Incorporating tissue-specific promoters in the vector design can ensure that the PTGFR gene is only expressed in the desired target tissues, reducing off-target effects.
Creative Biolabs offers expression control services. To manage the temporal pattern and magnitude of PTGFR expression, inducible promoters can be integrated into the gene therapy vector. For instance, promoters that are activated by particular chemical cues or environmental stimuli can be utilized to initiate or halt PTGFR expression according to requirements.
Creative Biolabs offers microRNA production services. Modifying the PTGFR gene so that it can be regulated by specific microRNAs can offer an extra level of control over gene expression. This method can be employed to precisely adjust the expression levels of PTGFR in various cell types or tissues.
Creative Biolabs offers comprehensive and innovative services to drive the development of PTGFR cell therapy. Please for more services.
Creative Biolabs offers receptor mutagenesis services. Perform site-directed mutagenesis on the PTGFR gene to create mutant receptors with altered activity or specificity. These mutants can be used to study receptor structure-function relationships and identify key residues for ligand binding and signaling.
Creative Biolabs offers chimeric receptors research services. Design chimeric receptors by fusing the PTGFR with other signaling domains or fluorescent tags. These chimeric receptors can be used to study receptor trafficking, localization, and signaling in real-time.
Creative Biolabs offers in vivo models production services. Create transgenic or gene-knockout animal models to explore the physiological function of PTGFR within living organisms. These models serve as valuable tools to assess the effectiveness and safety of therapies that specifically target PTGFR. Employ humanized mouse models to investigate the impacts of PTGFR regulation in a setting that more closely mimics clinical scenarios. These models can play a crucial role in narrowing the divide between pre-clinical and clinical research.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
