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Anti-GD3 ganglioside Antibody scFv (CAT#: MOM-18131-S(P))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human GD3 ganglioside Antibody scFv Fragment MOM-18131-S(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Chimeric (mouse/human) Antibody scFv Fragment specifically binds to Human GD3 ganglioside, expressed in E. coli
  • Target
  • GD3 ganglioside
  • Type
  • scFv Fragment from Chimeric (mouse/human) IgG1 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in ELISA, WB, Neut and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Purity
  • >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Introduction
  • This is a chimeric monoclonal antibody being developed for the treatment of malignant melanoma.
  • Antigen Description
  • Almost all melanomas, astrocytomas, a proportion of sarcomas, a small number of carcinomas, some nevi, as well as normal melanocytes express GD3 antigen. It is one of the most important markers for malignant melanoma. Antibodies to the GD3 ganglioside can induce partial remission of tumor growth in animals as well as in Humans via enhancement of cytotoxic and proliferative response of lymphocytes.
  • Keywords
  • GD3 ganglioside

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