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Custom SARS-CoV Virus-Like Particle (VLP) Production Service

Creative Biolabs is an undisputed world-leading service provider of VLP technology. With rich experience and well-established platforms, we can offer leading-edge VLP production service based on our advanced mammalian cells system and insect system to deliver diverse research goals.

Severe acute respiratory syndrome (SARS) was caused by a previously unrecognized animal coronavirus and adapt to become a virus readily transmissible between humans. SARS vaccine developments fall into several categories: inactivated SARS based vaccines, DNA or other recombinant viruses expressing the S spike glycoprotein subunit vaccines containing S receptor binding domain or soluble ectodomain and VLPs based vaccines. Of these, SARS VLP vaccine candidates have shown considerable promise. Recombinant VLP vaccine development has drawn increasing attention because it has the potential to be safer than inactivated or attenuated viral vaccines and to be more immunogenic than subunit or DNA vaccines.

Schematic structures of SARS-CoV.Fig.1 Structure and function of SARS-CoV.1

The structural proteins of SARS, including envelope glycoproteins spike (S), envelope (E), membrane (M) and nucleocapsid (N). With many years of experience in producing VLPs, Creative Biolabs can provide SARS-CoV VLPs composed of S, M, E or S, M, N, E in mammalian cells or insect cell expression system. The process details are always guided by the requirements of our customers. The general workflow includes:

Workflow of VLP production (Creative Biolabs Original).

Creative Biolabs has a wealth of expertise in VLP production and offers one-stop VLP construction services for diverse research/industrial needs. According to the structure of SARS, our scientists extend VLP production expertise to SARS and develop SARS VLP successfully. Creative Biolabs is proud to offer SARS VLP products, containing S/M/E or S/M/E/N to advance SARS research. Moreover, we provide VLP products labeled with GFP if clients want to put the dye marker for VLPs. Our professional experts are well-adept and pleased in tailoring the most reliable and cost-effective strategies for our customers to facilitate their significant research. Our excellent expert staff provides a variety of flexible and reliable solutions for our customers to facilitate their significant research. If you are interested in our services above, please feel free to contact us for more details.

Reference
  1. Kong, Xiaoyue, et al. "Recent advances in the exploration and discovery of SARS-CoV-2 inhibitory peptides from edible animal proteins." Frontiers in Nutrition 11 (2024): 1346510. Distributed under Open Access license CC BY 4.0, without modification.

All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

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