Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsWith our most devoted scientists and years of extensive experience in scaffold engineering, Creative Biolabs has gained significant knowledge in scaffold engineering. Our scientists are dedicated to offering first-class scaffold specificity optimization services to meet your specific requirements and speed up your research and project development.
Engineered scaffolds are invaluable tools for a broad range of applications due to their favorable modular structure, high affinity, excellent biophysical, and chemical properties. However, because of the sequence-relatedness of the target in different species or other similar proteins, scaffold may suffer low specificity to its target or unwanted cross-reactivity to other homologous proteins. To overcome this potential shortage, Creative Biolabs has established a rational system, that integrates in silico modeling and our advanced phage display platform, to preferably optimize the specificity of selected scaffolds. This system is particularly well suited to develop non-cross-reactive scaffolds and therefore contribute to increasing the targeting accuracy.
The utility of combining the phage display technology and in silico modeling provides a powerful tool to modify the binding loops of selected scaffolds for specificity improvement with required functions, which is critical to scaffold development. In this strategy, using in silico modeling and structural analysis, potential substitution residues could be identified by pinpointing key residues for site-specific optimization depending on the interaction of one scaffold with its target. Subsequently, a custom-designed mutant library can be constructed by rational design, and tailored pools of high-affinity variants are directed screened by surface display technology. With our extensive experience of in silico modeling and unparalleled expertise in phage display mutant library technology, Creative Biolabs focuses on the scaffold specificity optimization aiming at increasing the high specificity of scaffolds to its targets and eliminating unwanted cross-reactions.
With decades of experience and professional staff, our scientists at Creative Biolabs offer engineering scaffolds to deal with the urgent demands of every client for specificity optimization. Creative Biolabs also provides various other services related to engineering scaffolds. If you want more information about our specificity scaffold optimization services, please do not hesitate to contact us.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
