Target | PD-1 |
Immunogen | Recombinant protein of human PD-1 |
Species Reactivity | Human |
Application | ELISA, FC |
Clone | WJ41 |
Host Animal | Llama |
Isotype | sdAb |
Clonality | Monoclonal |
Class | Primary |
Concentration | 1 mg/mL |
Purification Method | Affinity chromatography purified via Nickel column. |
Conjugation | Unconjugated |
Buffer | PBS |
Physical State | Liquid |
Preservative & Stabilizer | 0.02% sodium azide |
Storage Condition | Store at -20°C for long term. |
Target Background | This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. |
Target Synonym | PDCD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1 |
Gene ID | 5133 |
UniProt ID | Q15116 |
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