Camelid Anti-SARS-CoV-2 RBD Single Domain Antibody (WJ727)(Cat#: MDWJ6933)
This product is a Camelid single domain antibody recognizes and binds the receptor-binding domain of SARS-CoV-2. This antibody showed substantial inhibition of RBD interaction with human angiotensin-converting enzyme 2 (ACE2). This product can be used in applications, such as ELISA, Inhib.
Datasheets| Target | SARS-CoV-2 |
| Immunogen | The receptor-binding domain of SARS-CoV-2 protein |
| Species Reactivity | SARS-CoV-2 |
| Application | ELISA, Inhib |
| Clone | WJ727 |
| Host Animal | Camelid |
| Isotype | sdAb |
| Clonality | Monoclonal |
| Class | Primary |
| Concentration | 1 mg/mL |
| Conjugation | Unconjugated |
| Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
| Target Background | The SARS-CoV-2 RBD has a twisted five-stranded antiparallel β sheet (β1, β2, β3, β4 and β7) with short connecting helices and loops that form the core. Between the β4 and β7 strands in the core, there is an extended insertion containing the short β5 and β6 strands, α4 and α5 helices and loops. In vitro binding measurements also showed that the SARS-CoV-2 RBD binds to ACE2 with an affinity in the low nanomolar range, indicating that the RBD is a key functional component within the S1 subunit that is responsible for binding of SARS-CoV-2 by ACE2. |
| Target Synonym | SARS-CoV-2 RBD; SARS-CoV-2 receptor-binding domain |
| Gene ID | 43740568 |
See other products for " SARS-CoV-2 "
KINDLY NOTE
- Some properties of custom products can be tailored flexibly. Please feel free to send your specific demands through an inquiry.
- All listed customized sdAb products are for lab research use only, not intended for pharmaceutical, diagnostic, therapeutic or any in vivo human use. For commercial purpose, please review our one-stop solutions for de novo sdAb discovery.
- No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
- NCBI/UniProt data is used to refer general target information. It may not necessarily be applicable to one specific product.
- Creative Biolabs has made every effort to ensure the accuracy of the datasheet and reserves the right to make changes to the datasheet at any time without prior notice. Creative Biolabs will not be liable for any omissions or errors contained herein, please use the COA of your custom products as standard.
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For Research Use Only. Not for diagnostic or therapeutic applications.
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