Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsSolute carrier family 52, also known as riboflavin transporter family (RFVT/SLC52), is composed of three riboflavin transporters: SLC52A1, SLC52A2, and SLC52A3. These transporters function by binding to riboflavin, which is a water-soluble vitamin also known as vitamin B2. These receptors have exhibited different distribution characteristics. SLC52A1 is highly expressed in the placenta and small intestine, SLC52A2 is expressed ubiquitously, especially higher in the brain and salivary gland. SLC52A3 is predominantly expressed in the testis and small intestine. As for substrate specificity, the three share a similar substrate specificity. However, the driving force of riboflavin transporters has not been clarified.
It has been strongly suggested that SLC52 transporters play important roles in riboflavin homeostasis. Moreover, polymorphisms in SLC52A1 and SLC52A3 could be the cause of two genetic diseases: riboflavin-responsive transient neonatal-onset MADD and BVVL syndrome, respectively. Further study of the SLC52 family is required to be conducted. Here, we give a brief summary of our current understanding of the human solute carrier family 52 members, including the structure, gene location, tissue distribution, substrate specificity, etc.
Technical limitations have long been a major hindrance to our understanding of the function and structure of membrane proteins. To help facilitate your scientific research, Creative Biolabs now introduces our cutting-edge Magic™ membrane protein production platform to help obtain your target proteins in their functional formats. Our technology platform has mastered both the classical approaches and newly emerged technologies in the field of membrane protein research. Our current techniques include detergent micelles, proteoliposomes, nanodiscs, lipoparticles, and membrane protein incorporation in polymers. Each method has both advantages and drawbacks and based on our combined expertise in biochemistry, we can always choose an optimal match for your protein.
As a pioneer in antibody discovery and engineering, Creative Biolabs proudly introduces our Magic™ membrane protein antibody discovery platform to help you with the development of anti-membrane protein antibodies using our diverse technologies. We also present DNA immunization service for anti-membrane protein antibody development. Please feel free to contact us for more information.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
