Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsSolute carrier family 12 (SLC12) consists of nine genes encoding seven functionally identified members and two orphan transporters. They are membrane transporters with a proposed Kyte-Dolittle topology of a hydrophilic short amino-terminal and long carboxyl-terminal domain. Studies have shown that an important characteristic of the SLC12 family is that the activity of all members is regulated by the phosphorylation/dephosphorylation of key serine/threonine residues located at the amino- and carboxy-terminal domains. Based on the degree of identity, this family is divided into two branches. The first includes the Na⁺ -coupled chloride cotransporters, including the Na⁺ :K⁺ :2Cl⁻ cotransporters 1 and 2 (NKCC1 and NKCC2) and the Na⁺ :Cl⁻ cotransporter (NCC), exhibiting about 50% identity amongst each other. The second branch is K⁺ -driven and encompasses four genes encoding the K⁺: Cl⁻ cotransporters (KCC1 through KCC4), which exhibit about 70% identity.
Here, we have described in detail of members of the SLC12 family, including but not limited to SLC12A1, SLC12A2, SLC12A3, and SLC12A4. To learn more detailed information, please click the links below.
Aided by our advanced MemDX™ membrane protein production platform, Creative Biolabs is committed to offering various target membrane protein products in required formats using various strategies, such as detergent micelles, proteoliposomes, nanodiscs, MP-VLPs, polymers, stable cell line.
In addition, our MemDX™ membrane protein antibody discovery platform can help to discover antibodies against these targets, even fully humanized antibodies, by various approaches such as hybridoma technology, phage display technology. We also present DNA immunization service for anti-membrane protein antibody development. To get more detailed information, please feel free to contact us.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
