Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsThe human solute carrier (SLC) transporters are central targets for drug development. Solute carrier family 18, also known as vesicular monoamine transporters (VMATs), is a class of transport proteins integrated into the membrane of synaptic vesicles of presynaptic neurons. Solute carrier family 18 consists of four members in human, referred to as SLC18A1 (VMAT1, synaptic vesicular amine transporter), SLC18A2 (VMAT2, synaptic vesicular amine transporter), SLC18A3 (vesicular acetylcholine transporter, VAChT), SLC18B1 (MFS-type transporter SLC18B1). They function to transport monoamine neurotransmitters including dopamine, norepinephrine, serotonin, epinephrine, and histamine into the vesicles which release the neurotransmitters into synapses as chemical messages to postsynaptic neurons. Members of solute carrier family 18 use a proton gradient generated by V-ATPases in vesicle membranes to power monoamine import.
Members of solute carrier family 18 have possible applications for many conditions and have been regarded as the sites of action of therapeutical drugs, such as tetrabenazine and reserpine. The biological research of solute carrier family 18 includes hypertension, drug addiction, psychiatric disorders, Parkinson's disease, and other neurological disorders. Here are the three members of the solute carrier family 18.
By using our MemDX™ membrane protein production platform, scientists at Creative Biolabs are well-experienced in providing the preparation services of these targets in required formats using various strategies, including detergent micelles, proteoliposomes, nanodiscs, MP-VLPs, polymers, with the stable cell line.
In addition, our MemDX™ membrane protein antibody discovery platform can also be applied in discovering antibodies against these targets, even fully humanized antibodies, by various approaches including hybridoma technology, phage display technology, and etc. We also present DNA immunization service for anti-membrane protein antibody development. Please feel free to contact us for more information.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
