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BR2 Pep-LNP

Cat. No.: TDLD-0825-LD94

BR2 Pep-LNP

BR2 Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the BR2 peptide, which interacts with specific receptors on the surface of target cells to facilitate precise localization and entry of the drug or nanocarrier into the target cell, particularly enhancing targeting efficiency in tumor therapy or gene therapy, this LNP offers enhanced specificity. Our LNP is prepared using DSPE-PEG-BR2 and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of BR2 Pep-LNP include targeted cancer therapy, developing receptor-specific imaging agents, enhancing the delivery of anti-cancer drugs or gene editing tools to tumors, and studying receptor-mediated endocytosis and drug delivery mechanisms in various disease models. Please note that this product is intended for research purposes only.

SPECIFIC INQUIRY
Payload:
Modification:
Lipid Formulation:
Dye:
Concentration:
Quantity:
Inquiry
For Research Use Only. Not for Diagnostic or Treatment Applications.
Payload Type mRNA
Payload Empty; EGFP mRNA; Firefly Luciferase mRNA; mCherry mRNA; GFP mRNA; OVA mRNA; EPO mRNA; Renilla Luciferase mRNA; Gaussia Luciferase mRNA; Beta-galactosidase mRNA; Cre mRNA; mOrange mRNA; tdTomato mRNA; EYFP mRNA
Capping Cap 1
Modification Unmodified; N1-methyl-pseudouridine; 5-methoxyuridine
Module Type Peptide
Targeting Module BR2 Peptide
Lipid Formulation DLin-MC3-DMA; LP-01; ALC-0315; SM102
Dye Unlabeled; DiR; DiD; DiO; DiI
Application Control; Targeted Delivery; Gene Therapy
Concentration 0.1 mg/mL; 0.2 mg/mL; Other (Please Specify)
Size 65-120 nm
PDI < 0.2
Zeta ± 20.0 mV
Encapsulate Efficiency >90%
Storage Store at 2-8°C
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