CD7-Targeted Ab-LNP (CD19 CAR mRNA)
Cat. No.: TDLD-0626-LD1
CD7-Targeted Ab-LNP (CD19 CAR mRNA)
CD7-Targeted Ab-LNP (CD19 CAR mRNA) is a state-of-the-art antibody-functionalized lipid nanoparticle (LNP). Engineered with the CD7 antibody, this LNP specifically recognizes and binds to the CD7 complex present on the surface of T cells, enabling highly selective targeting and internalization into CD7⁺ cell. This LNP encapsulates mRNA encoding the Chimeric Antigen Receptor (CAR) targeting CD19, serving as an excellent tool for investigating CAR-T cell therapies against CD19-positive B-cell malignancies, enabling studies on targeted immune interception and tumor microenvironment modulation. Our LNP ensures uniform particle size, high encapsulation efficiency, stability, and effective delivery. Applications of CD19 CAR mRNA-LNP include evaluating CAR expression on engineered T cells and assessing their cytotoxic activity against CD19-positive cancer cell lines. Please note that this product is intended for research purposes only.
| Payload Type | CAR mRNA |
| Payload | CD19 CAR mRNA |
| Module Type | Antibody |
| Targeting Module | CD7 Antibody |
| LNP Type | CAR mRNA-LNP |
| Target | CD7⁺ Cells |
| Lipid Formulation | DLin-MC3-DMA; LP-01; ALC-0315; SM102; Targeted Lipid (Please inquire) |
| Dye | Unlabeled |
| Application | Targeted Delivery; Gene Therapy; In Vivo CAR-T Engineering |
| Format | Liquid |
| Concentration | 0.1 mg/mL; 0.2 mg/mL; Other (Please Specify) |
| Size | 65-120 nm |
| PDI | < 0.2 |
| Zeta | ± 20.0 mV |
| Encapsulate Efficiency | >90% |
| Shipping | Dry Ice |
| Storage | Store at -80°C |
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