CGKRK Pep-LNP

Name: CGKRK Pep-LNP
SKU: TDLD-0825-LD75
Rating: 5 (1 reviews)

Datasheet

Cat. No.: TDLD-0825-LD75

CGKRK Pep-LNP

CGKRK Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the CGKRK peptide, this LNP possesses unique mitochondrial-targeting capabilities, as the CGKRK peptide is a mitochondrion-targeting peptide that can penetrate the cell membrane and guide associated markers or drugs to the mitochondria. Our LNP is prepared using DSPE-PEG-CGKRK and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of CGKRK Pep-LNP encompass research into mitochondrial diseases, cancer metabolism modulation, and other areas requiring direct intervention within the mitochondria. Please note that this product is intended for research purposes only.

SPECIFIC INQUIRY

Payload:

Modification:

Lipid Formulation:

Dye:

Concentration:

Quantity:

Inquiry

For Research Use Only. Not for Diagnostic or Treatment Applications.

Payload Type	mRNA
Payload	Empty; EGFP mRNA; Firefly Luciferase mRNA; mCherry mRNA; GFP mRNA; OVA mRNA; EPO mRNA; Renilla Luciferase mRNA; Gaussia Luciferase mRNA; Beta-galactosidase mRNA; Cre mRNA; mOrange mRNA; tdTomato mRNA; EYFP mRNA
Capping	Cap 1
Modification	Unmodified; N1-methyl-pseudouridine; 5-methoxyuridine

Module Type	Peptide
Targeting Module	CGKRK Peptide

Target	Mitochondrion
Lipid Formulation	DLin-MC3-DMA; LP-01; ALC-0315; SM102
Dye	Unlabeled; DiR; DiD; DiO; DiI
Application	Control; Targeted Delivery; Gene Therapy
Concentration	0.1 mg/mL; 0.2 mg/mL; Other (Please Specify)

Size	65-120 nm
PDI	< 0.2
Zeta	± 20.0 mV
Encapsulate Efficiency	>90%

Storage

Store at 2-8°C