Cy5-labeled Fluc mRNA-LNP
Cat. No.: TDLD-0825-LD23
Cy5-labeled Fluc mRNA-LNP
Cy5-labeled Fluc mRNA-LNP is a state-of-the-art messenger RNA (mRNA) lipid nanoparticle (LNP) system, specifically engineered for efficient in vitro and in vivo protein expression. This LNP encapsulates mRNA encoding Firefly Luciferase (Fluc), serving as an excellent tool for dual-modality imaging, enabling the correlation of bioluminescence signals with nanoparticle localization and uptake in real-time. Engineered with a proprietary lipid formulation for optimal mRNA encapsulation and delivery, it ensures high translation efficiency. We offer flexibility in lipid composition, including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and targeted lipids for specific tissues (lung, liver, spleen, muscle), allowing for tailored delivery strategies. Our LNP ensures uniform particle size, high encapsulation efficiency, stability, and effective delivery. Applications of Cy5-labeled Fluc mRNA-LNP include validating transfection efficiency and spatial distribution in cell culture and animal models, studying kinetics of gene expression and nanoparticle clearance, performing longitudinal monitoring of disease progression or therapeutic response, and serving as a powerful platform for preclinical drug development and imaging probe evaluation. Please note that this product is intended for research purposes only.
| Payload Type | mRNA |
| Payload | Cy5-labeled Firefly Luciferase mRNA |
| Capping | Cap 1 |
| Modification | Unmodified; N1-methyl-pseudouridine; 5-methoxyuridine; Other |
| Module Type | Unconjugation |
| LNP Type | mRNA-LNP |
| Lipid Formulation | DLin-MC3-DMA; LP-01; ALC-0315; SM102; Targeted Lipid (Please inquire) |
| Dye | Unlabeled; DiR; DiD; DiO; DiI; Other |
| Application | Tracking & Imaging; Gene Therapy |
| Format | Liquid |
| Concentration | 0.1 mg/mL; 0.2 mg/mL; Other (Please Specify) |
| Size | 65-120 nm |
| PDI | < 0.2 |
| Zeta | ± 20.0 mV |
| Encapsulate Efficiency | >90% |
| Shipping | Dry Ice |
| Storage | Store at -80°C |
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