Creative Biolabs

Fluc mRNA-LNP

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Cat. No.: TDLD-0825-LD11

Fluc mRNA-LNP

Fluc mRNA-LNP is a state-of-the-art messenger RNA (mRNA) lipid nanoparticle (LNP) system, specifically engineered for efficient in vitro and in vivo protein expression. This LNP encapsulates mRNA encoding the Firefly Luciferase (Fluc) reporter gene, serving as an excellent tool for quantitatively assessing gene delivery efficiency and tracking expression levels in real-time using bioluminescence imaging techniques. Engineered with a proprietary lipid formulation for optimal mRNA encapsulation and delivery, it ensures high translation efficiency. We offer flexibility in lipid composition, including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and targeted lipids for specific tissues (lung, liver, spleen, muscle), allowing for tailored delivery strategies. Our LNP ensures uniform particle size, high encapsulation efficiency, stability, and effective delivery. Applications of Fluc mRNA-LNP include evaluating LNP transfection efficacy, studying gene expression kinetics, monitoring cellular uptake, and serving as a reporter system in drug development and basic research. Please note that this product is intended for research purposes only.

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For Research Use Only. Not for Diagnostic or Treatment Applications.
Payload Type mRNA
Payload Firefly Luciferase mRNA
Capping Cap 1
Modification Unmodified; N1-methyl-pseudouridine; 5-methoxyuridine; Other
Module Type Unconjugation
Lipid Formulation DLin-MC3-DMA; LP-01; ALC-0315; SM102; Targeted Lipid (Please inquire)
Dye Unlabeled; DiR; DiD; DiO; DiI; Other
Application Tracking & Imaging; Gene Therapy
Format Liquid
Concentration 0.1 mg/mL; 0.2 mg/mL; Other (Please Specify)
Size 65-120 nm
PDI < 0.2
Zeta ± 20.0 mV
Encapsulate Efficiency >90%
Shipping Dry Ice
Storage Store at -80°C

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Customer Review

Creatibe Biolabs' custom LNP was the only solution that successfully delivered our CRISPR-Cas9 payload across the blood-brain barrier with high efficiency and low toxicity.”

Dr. Evelyn Reed

Postdoctoral Researcher, Leading University

Our siRNA candidate was failing due to off-target toxicity, but Creatibe Biolabs' team rapidly redesigned our LNP using their modular platform, rescuing our preclinical program.”

Ben Carter

Project Manager

Achieving cytosolic delivery of our protein degrader with Creatibe Biolabs' exosome platform was the key to unlocking our candidate's full therapeutic potential.”

Dr. Kenji Tanaka

Principal Scientist, Large Pharma Corp

Our oncology drug's efficacy was limited by poor tumor accumulation. Creatibe Biolabs' peptide-conjugated liposomes provided the precise targeting we needed, dramatically increasing the drug's therapeutic index.”

Dr. Clara Schmidt

Senior Scientist, Oncology Innovations Inc.

We required a delivery system that would only release its payload in the tumor's acidic microenvironment. Creatibe Biolabs' pH-responsive liposomes performed flawlessly, minimizing systemic exposure.”

David Chen

Formulation Scientist

Outstanding expertise in antibody engineering.The team's attention to detail and innovative approaches have sianificantly accelerated our development timeline.

Sarah L.

Senior Research Scientist

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