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FSHB Pep-LNP

Cat. No.: TDLD-0825-LD95

FSHB Pep-LNP

FSHB Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the FSHB peptide, a specific fragment of the Follicle Stimulating Hormone β-subunit that recognizes the FSH receptor (FSHR) widely expressed on ovarian cancer cells, testicular Sertoli cells, and certain reproductive system tumor cells, this LNP offers enhanced specificity for these tissues. Our LNP is prepared using DSPE-PEG-FSHB and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of FSHB Pep-LNP include targeted therapy for ovarian cancer and other FSHR-expressing reproductive system malignancies, developing FSHR-specific imaging agents, studying the biology of FSH signaling in reproductive tissues, and potentially modulating fertility-related processes. Please note that this product is intended for research purposes only.

SPECIFIC INQUIRY
Payload:
Modification:
Lipid Formulation:
Dye:
Concentration:
Quantity:
Inquiry
For Research Use Only. Not for Diagnostic or Treatment Applications.
Payload Type mRNA
Payload Empty; EGFP mRNA; Firefly Luciferase mRNA; mCherry mRNA; GFP mRNA; OVA mRNA; EPO mRNA; Renilla Luciferase mRNA; Gaussia Luciferase mRNA; Beta-galactosidase mRNA; Cre mRNA; mOrange mRNA; tdTomato mRNA; EYFP mRNA
Capping Cap 1
Modification Unmodified; N1-methyl-pseudouridine; 5-methoxyuridine
Module Type Peptide
Targeting Module FSHB Peptide
Target Ovarian cancer
Lipid Formulation DLin-MC3-DMA; LP-01; ALC-0315; SM102
Dye Unlabeled; DiR; DiD; DiO; DiI
Application Control; Targeted Delivery; Gene Therapy
Concentration 0.1 mg/mL; 0.2 mg/mL; Other (Please Specify)
Size 65-120 nm
PDI < 0.2
Zeta ± 20.0 mV
Encapsulate Efficiency >90%
Storage Store at 2-8°C
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