HER3 CAR mRNA-LNP
Cat. No.: TDLD-0825-LD44
HER3 CAR mRNA-LNP
HER3 CAR mRNA-LNP is a state-of-the-art messenger RNA (mRNA) lipid nanoparticle (LNP) system, specifically engineered for efficient in vitro and in vivo protein expression. This LNP encapsulates mRNA encoding the Chimeric Antigen Receptor (CAR) targeting Human Epidermal growth factor Receptor 3 (HER3), serving as an excellent tool for investigating novel CAR-T cell therapies against HER3-expressing cancers, particularly those with HER2 amplification, and for studying receptor-specific immune modulation in oncology research. Engineered with a proprietary lipid formulation for optimal mRNA encapsulation and delivery, it ensures high translation efficiency. Our LNP ensures uniform particle size, high encapsulation efficiency, stability, and effective delivery. Applications of HER3 CAR mRNA-LNP include monitoring CAR expression on transduced T cells and evaluating CAR-T cell functionality against HER3-positive targets. Please note that this product is intended for research purposes only.
| Payload Type | CAR mRNA |
| Payload | HER3 CAR mRNA |
| Modification | Unmodified; N1-methyl-pseudouridine; 5-methoxyuridine; Other |
| Module Type | Unconjugation |
| Lipid Formulation | SM102 |
| Dye | Unlabeled |
| Application | Gene Therapy; CAR-T |
| Format | Liquid |
| Concentration | 0.1 mg/mL; 0.2 mg/mL; Other (Please Specify) |
| Size | 65-120 nm |
| PDI | < 0.2 |
| Zeta | ± 20.0 mV |
| Encapsulate Efficiency | >90% |
| Shipping | Dry Ice |
| Storage | Store at -80°C |
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